نتایج جستجو برای: cancerous model

تعداد نتایج: 2111470  

Journal: :Oncology reports 2009
Tsuyoshi Chijiwa Yoshiyuki Abe Yoshimasa Inoue Hozumi Matsumoto Kenji Kawai Masahiro Matsuyama Noriyuki Miyazaki Hiroshi Inoue Masaya Mukai Yoshito Ueyama Masato Nakamura

Thrombospondin (TSP)-2 is known to be an endogenous negative regulator of vascularization in human cancer. However, it is unclear whether TSP-2 expression is related to neovascularization and prognosis in non-small cell lung cancer. In this study, we quantitatively examined the expression of TSP-2 mRNA by real-time reverse transcription-polymerase chain reaction (RT-PCR) in 102 pulmonary adenoc...

Journal: :The Journal of biological chemistry 1978
B Siddiqui J S Whitehead Y S Kim

Glycosphingolipids were analyzed from colonic tumors and histologically normal adjacent tissues, obtained at surgery from eight patients. Detailed analysis was carried out on six neutral glycolipids from normal colonic mucosa and cancerous tissues. Their structures were established by permethylation, use of glycosidases, and immunological methods. In the cancerous tissues, lactosylceramide was ...

2011
Cheng-Ye Wang Hui Li Xiao-Dan Hao Jia Liu Jia-Xin Wang Wen-Zhi Wang Qing-Peng Kong Ya-Ping Zhang

In the past decade, a high incidence of somatic mitochondrial DNA (mtDNA) mutations has been observed, mostly based on a fraction of the molecule, in various cancerous tissues; nevertheless, some of them were queried due to problems in data quality. Obviously, without a comprehensive understanding of mtDNA mutational profile in the cancerous tissue of a specific patient, it is unlikely to discl...

Journal: :The Tohoku Journal of Experimental Medicine 1987

2016
J. O'Brien

? some 4 months ago. A small sore resulted, which, instead of healing, has gone on steadily increasing in size. There is a good deal of shooting pain, difficulty in speaking and swallowing, and much distress generally. On admission into the Medical College Hospital a few days ago a large epithelioma with cracked fungating base and indurated everted edges was seen occupying the right side of ton...

2015
Gregory Lee

The expression of immunoglobulins by cancer cells have been known for two decades. However, the mechanisms of action behind these cancerous immunoglobulins (cIgG) are not well understood and may be different from immunoglobulins secreted by normal B lymphocytes. Therefore, the structural and functional roles of cIgG have been actively investigated to resolve this mystery. A monoclonal antibody,...

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