The antimicrobial activity of five sanitizing agents employed in clean areas designated for the pharmaceutical manufacturing of sterile products was tested against nine microorganisms, including four microorganisms from the clean area microbiota. The method consisted of challenging 5 mL of each sanitizing agent 70% isopropyl alcohol, 0.4% LPH®, 1.16% hydrogen peroxide, 4% hydrogen peroxide, 1% ...

The present study aims to investigate the antimicrobial and antitumor properties of Ganoderma lucidum fruit bodies grown under tropical habitat. The phytochemicals present in Ganoderma sp. DKR1 were analyzed and identified as saponins, tannins, terpenoids and phlobatannins. The bioactive compounds in Ganoderma sp. DKR1 were extracted using the solvents (ethyl acetate and chloroform). Its antimi...

The correct identification of Candida species is of great importance, as it presents prognostic and therapeutical significance, allowing an early and appropriate antifungical therapy. The purpose of this study was to identify isolates of Candida spp. from oral mucosa of 38 patients with oral candidosis evaluated in 2004 by phenotypic methods and PCR, discriminating C. albicans from the other Ca...

Candida sp. are opportunistic fungal pathogens that colonize the skin and oral cavity and, when overgrown under permissive conditions, cause inflammation and disease. Previously, we identified a central role for the NLRP3 inflammasome in regulating IL-1β production and resistance to dissemination from oral infection with Candida albicans. Here we show that mucosal expression of NLRP3 and NLRC4 ...

BACKGROUND AND OBJECTIVES Biodeterioration is an irreversible damage that is caused by colonization of microorganisms on the surface of different materials. Among all microorganisms, fungi play an important role in deterioration of materials. Fungi can colonize on stone surfaces and by secreting different enzymes, organic and inorganic acids and pigments, can cause bio-weathering and changing n...

The aim of this study was to analyse polar lipids of Candida species isolated from Ahwaz (Iran) by Fast Atom Bombardment Mass Spectrometry (FAB MS). Nine isolates of Candida Sp. were identified by growth at 45°C, production of chlamydoconidia on cornmeal agar, colonial colour on CHROMagar Candida, germ tube production and ID 32C kits. Then polar lipids were extracted from freeze-dried cult...

Penyakit yang disebabkan oleh mikroba patogen telah menginfeksi makhluk hidup seperti manusia, hewan, dan tanaman. Hal ini memberikan dampak negatif bagi kesehatan manusia menurunkan kualitas produksi di bidang pertanian. Agen biokontrol dapat digunakan untuk mencegah infeksi aman ramah lingkungan. Penelitian bertujuan mengetahui potensi dari bakteri Streptomyces sp. strain i18 sebagai agen dal...