Serum transferrin is a key player in iron homeostasis, and its ability to deliver iron to cells via the endosomal pathway critically depends on the presence of carbonate that binds this protein synergistically with ferric ion. Oxalate is another ubiquitous anionic species that can act as a synergistic anion, and in fact its interaction with transferrin is notably stronger compared to carbonate,...

Reliable prediction of freezing point depression in liquid electrolytes will accelerate the development improved Li-ion batteries which can operate low temperature environments. In this work we establish a computational methodology to calculate activity coefficients and liquidus lines for battery-relevant electrolytes. Electronic structure methods are used conjuction with classical molecular dy...

During an acute fall in systemic pH due to a decrease in the concentration of serum bicarbonate ([HCO(3)(-)]), metabolic acidosis, there is an influx of hydrogen ions into the mineral phase of bone, buffering the decrement in pH. When bone is cultured in medium modeling acute metabolic acidosis, the influx of hydrogen ions is coupled to an efflux of sodium and potassium and a depletion of miner...

using solvent evaporating and atomic emission spectrophotometric methods, the solubility of li2co3 in waterat 25°c was determined. comparing the value of thermodynamic solubility product constant, ksp(th),(ksp(tn) = exp(—ag.ss/rt)) of the mentioned salt to the value which is obtained from the observed solubility,shnoll-1 , and activity coefficients, f+ and f, which are estimated upon the extend...

Characterizing fundamental ion transport is necessary for the modification and development of electrolytes. In this study, we investigated local bulk properties 1 M NaPF6 in binary EC:PC (1:1), ternary 5EC:3PC:2DEC (5:3:2) solvents, as well their 2 wt.% FEC modulated versions. We determined 1H, 19F 23Na Nuclear Magnetic Resonance (NMR) spin-lattice relaxation time (T1), self-diffusion coefficie...