Although much CFD work has been carried out to study the blood damage created in a centrifugal pump used for a cardiopulmonary bypass, little is known about the blood flow and consequent damage in a roller pump. A timedependent moving boundary problem is solved in this paper to explore the blood flow and damage in the roller pump. An initial attempt to predict the blood damage from these simula...

During cardiopulmonary bypass (CPB) the concentration of blood components is controlled by fluid administration and diuresis. However, diuresis is not always adequate and at the end of CPB the diluted pump blood, unless processed by expensive and cumbersome RBC saving techniques, is usually discarded. To control "diuresis" during CPB and to concentrate all blood components of the diluted pump b...

OBJECTIVE Activation of innate immunity cells is inseparably linked to cardiac surgical operation. The aim of this study was to assess the kinetics in the expression of receptor for Fc part of IgG, FcgammaRI (CD64), and scavenger receptor CD163 on peripheral blood cells of cardiac surgical patients and to examine the effect of cardiac bypass as a separable influence on the systemic acute inflam...

BACKGROUND We compared the outcomes in propensity score-matched high-risk patients (European System for Cardiac Operative Risk Evaluation [EuroSCORE] ≥ 5) undergoing off-pump coronary artery bypass graft surgery using bilateral or single skeletonized internal thoracic artery (ITA). METHODS AND RESULTS Of 794 consecutive patients undergoing isolated coronary artery bypass graft surgery (788 by...

abstract background: aprotinin has been used increasingly to reduce postoperative blood loss in open-heart operations due to the potentialities for complications and high cost, it would seem reasonable to use aprotinin more selectively in small doses in the prime solution of the pump. methods: we prospectively studied the effect of preoperative low dose aprotinin [2 million units (230mg)] on bl...

patients and methods sixty children aged between 2 and 12 years, and scheduled for on-pump surgery due to a congenital heart disease were randomly assigned into two groups. oral midazolam (0.5 mg/kg up to 15 mg per patient) and dexmedetomidine (2 µg/kg) were administered 45 minutes pre-anesthesia. children’s anxiety, mask acceptance behavior, hemodynamic measures, and cardiopulmonary outcomes w...

Background—We compared the outcomes in propensity score-matched high-risk patients (European System for Cardiac Operative Risk Evaluation [EuroSCORE] 5) undergoing off-pump coronary artery bypass graft surgery using bilateral or single skeletonized internal thoracic artery (ITA). Methods and Results—Of 794 consecutive patients undergoing isolated coronary artery bypass graft surgery (788 by the...

Vacuum-assist venous drainage (VAVD) can increase venous blood return during cardiopulmonary bypass (CPB) procedures. However, the negative pressure created in the closed cardiotomy reservoir can be transmitted to the oxygenator if a nonocclusive or centrifugal arterial pump is used, resulting in bubble transgression (BT) from the gas to blood compartment of the oxygenator. We analyzed the vacu...

BACKGROUND Coronary artery bypass graft (CABG) surgery is one of the most commonly performed surgical procedures worldwide, and it may be accompanied by postoperative neurocognitive impairment. Although this complication has been attributed to the use of cardiopulmonary bypass, it is still a matter of debate whether the switch from on-pump to off-pump technique affects the cognitive function. ...