objective(s): in this study, for the first time, mf59 adjuvant was used to develop a cholesteryl ester transfer protein (cetp) vaccine. the efficacy of the vaccine was compared with the efficacy of cetp vaccine formulated with alum/cpg, the formulation that its immunogenicity has been already demonstrated in rabbit and mice. materials and methods: tetanus toxoid- cetp peptide (tt-cetp) was mixe...

background: little is known about the effects of a low energy dense diet on weight maintenance and cardiovascular risks following a recent weight reduction. therefore, we assessed if weight maintenance, lipid profiles, and glycemic control differ between low energy density (led) diet and usual diet consumers following a recent weight reduction. materials and methods: in this randomized controll...

background: ratio of second and fourth digit (2d:4d) is known to be germane in analyzing utero concentrations of testosterone and estrogen in human and other vertebrates. 2d:4d had been linked several traits like athletes’ abilities, reproductive success, risk of cancer and cardiovascular disease (cvd). metabolic syndrome (mets) is a clustering of several cardiovascular risk factors. waist ci...

background: metabolic syndrome (ms) is the syndrome closely related to cardiovascular disease (cvd) risk factors. few prospective studies have compared the impact of dynamic changes of ms on the development of cardiovascular diseases (cvd). methods: overall, 3461 subjects were recruited from a cohort study on prevention of multiple metabolic disorders and ms in jiangsu of china (pmmjs) with a f...

background postprandial lipemia has been found to be strongly associated with atherosclerosis due to its atherogenic and thrombogenic lipoprotein changes. this phenomenon occurs even in normal subjects especially after high fat meals. orlistat, an anti- obesity drug, has been shown to address postprandial lipemia after a single high fat meal. objectives to compare the effects of orlistat and pl...

The effects of psychological and behavioral factors on physical illness are increasingly recognized. For example, depression and anger have repeatedly been reported as key predictors of a poor recovery following myocardial infarction, independent of specific disease indices.1–3 Depression, anticipatory nausea, and anxiety are often common in cancer patients.4–8 Depression and anxiety have also ...

Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL; Program in Gastronomy, Culinary Arts, and Wine Studies, Boston University and Program in Environmental Studies, Harvard University, Boston, MA; Division of Cardiovascular Disease, School of Medicine, University of Alabama at Birmingham, Birmingham, AL; Dept of Biostatistics, School of Publi...