The eukaryotic CMG (Cdc45, Mcm2-7, GINS) helicase consists of the Mcm2-7 hexameric ring along with five accessory factors. The Mcm2-7 heterohexamer, like other hexameric helicases, is shaped like a ring with two tiers, an N-tier ring composed of the N-terminal domains, and a C-tier of C-terminal domains; the C-tier contains the motor. In principle, either tier could translocate ahead of the oth...

Guoli Wang,1,2 Cheng Jin,2 Anh-Thu Le,2 and C. D. Lin2 1Key Laboratory of Atomic and Molecular Physics and Functional Materials of Gansu Province, College of Physics and Electronic Engineering, Northwest Normal University, Lanzhou 730070, China 2J. R. Macdonald Laboratory, Physics Department, Kansas State University, Manhattan, Kansas 66506-2604, USA (Received 29 February 2012; published 10 Jul...

This paper examines feasibility and performance issues in using Control Moment Gyroscopes (CMGs) to control the attitude of a fixed-wing aircraft. The paper describes a control system structure that permits allocating control authority and bandwidth between a CMG system and conventional aerodynamic control surfaces to stabilize a vehicle with neutral aerodynamic stability. A simulation study ex...

-Backward recognition masking refers to interference of a second masking tone with recognition of a target tone presented earlier in time. The degree of interference has been found to decrease as the length. of the silent interval separating the two tones increases. These results have been interpreted as representing interference of the masking tone upon the preperceptual storage and perceptual...

Replicative helicases are ring-shaped hexamers that encircle DNA for duplex unwinding. The currently accepted view of hexameric helicase function is by steric exclusion, where the helicase encircles one DNA strand and excludes the other, acting as a wedge with an external DNA unwinding point during translocation. Accordingly, strand-specific blocks only affect these helicases when placed on the...

The eukaryotic replicative DNA helicase, CMG, unwinds DNA by an unknown mechanism. In some models, CMG encircles and translocates along one strand of DNA while excluding the other strand. In others, CMG encircles and translocates along duplex DNA. To distinguish between these models, replisomes were confronted with strand-specific DNA roadblocks in Xenopus egg extracts. An ssDNA translocase sho...

Akinori Igarashi1 and C. D. Lin2 1Department of Applied Physics, Faculty of Engineering, Miyazaki University, Miyazaki, 889-2192, Japan 2Department of Physics, Cardwell Hall, Kansas State University, Manhattan, Kansas 66506 (Received 18 May 1999) Cross sections for the nonresonant charge transfer process D 1 H 1s ! D 1s 1 H at low energies are calculated in hyperspherical coordinates. The metho...