نتایج جستجو برای: cd95l

تعداد نتایج: 278  

Journal: :Journal of immunology 1999
M Shimizu A Fontana Y Takeda H Yagita T Yoshimoto A Matsuzawa

Fas/Apo-1 (CD95)-Fas ligand (FasL) system has been implicated in the suppression and stimulation of immune responses. We examined the induction of antitumor immunity with neuroblastoma Neuro-2a cells transfected with FasL cDNA (Neuro-2a+FasL). Neuro-2a+FasL cells expressed FasL on the cell surface and secreted soluble FasL. Histologic and flow cytometric analyses revealed that Neuro-2a+FasL cel...

2011
Peter H. Krammer Andreas Ludwig Elisabeth Suri-Payer Nina Oberle Katharina Lahl Christian T. Mayer Tim Sparwasser Eva-Maria Weiss Angelika Schmidt Diana Vobis Natalio Garbi

Journal: :Blood 2011
Yang Wang Mingwan Su Liang L Zhou Ping Tu Xuejun Zhang Xiaoyan Jiang Youwen Zhou

Sézary syndrome (SS) is an aggressive subtype of cutaneous T-cell lymphoma that is characterized by circulating leukemic Sézary cells. The accumulation of these malignant cells has been shown to be the result of the resistance to apoptosis, in particular, activation-induced cell death. However, the mechanism of apoptosis resistance remains unknown. By characterizing the gene transcription profi...

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