Connected Dominating Sets (CDSs) can serve as virtual backbones for wireless networks. A smaller virtual backbone (minimum size CDS) incurs less communication overhead. Unfortunately, computing a minimum size CDS is NP-hard and thus many algorithms were developed which concentrates on how to construct smaller CDSs. Aiming for minimum number of nodes in CDS, results in CDSs that are highly unsta...

Clinical decision support systems (CDSS) use data from a variety sources to provide guidance to physicians at the point of care. However, several studies have shown that data from these registries often can not be trusted to be accurate or complete. For instance, studies show that accuracy and completeness in medical registries may be as low as 67% and 30.7%, respectively. Consequently, since C...

We searched for 2,563 microRNA (miRNA) binding sites in 17,494 mRNA sequences of human genes. miR-1322 has more than 2,000 binding sites in 1,058 genes with ΔG/ΔG m ratio of 85% and more. miR-1322 has 1,889 binding sites in CDSs, 215 binding sites in 5' UTRs, and 160 binding sites in 3' UTRs. From two to 28 binding sites have arranged localization with the start position through three nucleotid...

We propose CONFlexFlow (Clinical cONtext based Flexible workFlow) as a novel approach for integrating clinical pathways into Clinical Decision Support Systems (CDSS). It recognizes that clinical pathways involve frequent deviations and require considerable flexibility. Thus, integration of flexible pathways is critical for the success of CDSS. Further, it is based on a better understanding of c...

BACKGROUND Poor quality of care is among the causes of high maternal and newborn disease burden in Tanzania. Potential reason for poor quality of care is the existence of a "know-do gap" where by health workers do not perform to the best of their knowledge. An electronic clinical decision support system (CDSS) for maternal health care was piloted in six rural primary health centers of Tanzania ...

IntroductIon Clinical decision-making is a complex process that is reliant on accurate and timely information. Clinicians are dependent (or should be dependent) on massive amounts of information and knowledge to make decisions that are in the best interest of the patient. Increasingly, information technology (IT) solutions are being used as a knowledge transfer mechanism to ensure that clinicia...

Credit default swaps (CDSs) are thought to ease borrowing by protecting lenders against default. This paper develops a model of the demand for CDS when borrowers choose the riskiness of investment and verification is imperfect. The model shows that CDSs may lead to risk-shifting, increasing the probability of default. Our model provides new insights on the role of CDS during the recent financia...

Based on a review of domestic and foreign research, application status, classification, composition, and the main problem of a clinical decision support system, this paper proposed a CDSS mode based on a knowledge base. On KB-CDSS mode, this paper discussed the architecture, principle, process, construction of the knowledge base, system design, and application value, then introduced the applica...

In this paper, we consider the hedging of portfolio loss derivatives using single-name credit default swaps as hedging instruments. The hedging issue is investigated in a general pure jump dynamic setting where default times are assumed to admit a joint density. In a first step, we compute default intensities adapted to the global filtration of defaults. In particular, we stress the impact of a...