Background: We had previously identified the genes involved in squamous cell carcinoma of the head and neck using differential display and DNA microarray techniques. We also reported the first analytical study on a novel human gene called LOC92912, which was identified by differential display as a gene up-regulated in such carcinomas. LOC92912, which is a putative member of the E2 ubiquitin con...

The appropriate temperature and growth supplementary factors such as fetal bovine serum (FBS) are the necessities needed for cell growth in culture medium. In this regards, the effect of Leibovitz-15 (L-15) medium containing different concentrations of fetal bovine serum (FBS) was assessed on growth and proliferation of cultivated liver cells of klunzingerchr('39')s mullet, Liza klunzingeri, in...

Nanofibrillar Hydrogels for Cell Growth In article number 2002202, Andre G. Skirtach and co-workers develop nanofibrillar hydrogels by a new simple self-assembly procedure upon thermal annealing that is shown to be an effective cell growth platform. Biological medical implications of structures are discussed. Developing materials linked with insights into growth, understanding interfaces cell–s...

Background: Growth plate is responsible for bone elongation and its injury could result in severe orthopedic problems. OBJECTIVES: This study was aimed to investigate the radiographic changes after transplanting the fresh autogenous ear cartilage impregnated with PRP and MSc in treatment of growth plate injury in lamb. METHODS: Cranial half (½) in length in full depth of the right hind limb gro...

objective: silybin is a polyphenol with anti-oxidant and anti-cancer properties. the poor bioavailability of some polyphenols can be improved by binding to phosphatidylcholine. in recent years, studies have been conducted to evaluate the anti-cancer effect of silybin. we studied the effect of silybin and silybin-phosphatidylcholine on esr1 and esr2 gene expression and viability in the t47d brea...

introduction: embryonic stem (es) cells are pluripotent cells derived from inner cell mass of blastocyst. these cells can product any cell by spontaneous or directed differentiation. this study was started to produce neuron cells by directed differentiation of new murine es cell line in vitro. materials and methods: murine es cells (royan b1 derived from c57bl/6 strain) were used for in vitro n...

transforming growth factor betas are multifunctional polypeptides in the cytokine superfamily. they have a growth inhibitory role on hemopoietic progenitor cells in semisolid colony assay as well as in long-term bone-marrow culture. tgf - β2 represses stromal cells, stem cell factor gene transcription, and decreases the stability of c-kit transcripts in hemopoietic cells. tgf-β also modulates g...

objective: perovskia abrotanoides karel, belongs to the family lamiaceae and grows wild alongside the mountainous roads inarid and cold climate of northern iran. the anti-tumor activity of p. abrotanoides root extract has been shown previously. this study was designed to examine in vitro anti-proliferative and pro-apoptotic effects of flower extract of p. abrotanoides on mcf-7 and hela cell lin...