7 Matthew R. Hodges and George B. Richerson 8 9 Dept of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226 10 11 Departments of Neurology and Cellular and Molecular Physiology, 12 Yale University, New Haven, CT 06520 13 14 Veteran’s Affairs Medical Center, West Haven, CT 06516 15 16 Address for Correspondence: 17 Matthew R. Hodges 18 BSB-504, Dept of Physiology 19 Medical College of ...

The calcium-sensing receptor (CaSR) has played an important role as a target in the treatment of a variety of disease states over the past 20 plus years. In this review, we give an overview of the receptor at the cellular level and then provide details as to how this receptor has been targeted to modulate cellular ion transport mechanisms. As a member of the G protein-coupled receptor (GPCR) fa...

7 Matthew R. Hodges and George B. Richerson 8 9 Dept of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226 10 11 Departments of Neurology and Cellular and Molecular Physiology, 12 Yale University, New Haven, CT 06520 13 14 Veteran’s Affairs Medical Center, West Haven, CT 06516 15 16 Address for Correspondence: 17 Matthew R. Hodges 18 BSB-504, Dept of Physiology 19 Medical College of ...

1 Guidelines in Cardiovascular Research; a First for the American Journal of 2 Physiology: Heart and Circulatory Physiology 3 4 Irving H. Zucker 5 University of Nebraska Medical Center 6 Omaha, NE 7 8 9 10 Running title: Guidelines papers 11 12 Correspondence: 13 Irving H. Zucker, Ph.D. 14 Department of Cellular and Integrative Physiology 15 University of Nebraska Medical Center 16 985850 Nebra...

Background: The incidence of diabetes mellitus is rapidly increasing in the world. One of the complications of diabetes includes disturbance of the reproductive tract, such as infertility, erectile dysfunction, and endocrine disturbances. Nitric oxide (NO) is a free radical produced by most of cells including the human male and female reproductive tracts. NO has a dual role where low concentrat...