Title Evaluation of Echinococcus multilocularis tetraspanins as vaccine candidates against primary alveolar echinococcosis Author(s) Dang, Zhisheng; Yagi, Kinpei; Oku, Yuzaburo; Kouguchi, Hirokazu; Kajino, Kiichi; Watanabe, Junichi; Matsumoto, Jun; Nakao, Ryo; Wakaguri, Hiroyuki; Toyoda, Atsushi; Sugimoto, Chihiro Citation Vaccine, 27(52): 7339-7345 Issue Date 2009-12-09 Doc URL http://hdl.hand...

Echinococcus multilocularis, the zoonotic agent of human alveolar echinococcosis, has considerably extended its range and became more prevalent in many parts of the endemic areas. Accordingly, there is an increasing demand for measures to prevent human infections. Rising public awareness of this zoonosis and individual protective actions should be part of every prevention program. Considering t...

Over the last decade, studies have begun to shed light on the distribution and genetic characterization of Echinococcus multilocularis, the causative agent of alveolar echinococcosis (AE), in North America. Recent findings indicate that the parasite is likely expanding its range in the central region of the United States and Canada and that invasions of European strains might have occurred. In ...

We read with great interest Karaman et al.’s rare case concerning lung infection with Echinococcus alveolaris [1]. We would like to highlight two points concerning the conservative treatment and imaging characteristics of alveolar echinococcosis (AE). AE is a severe disease, with a mortality of over 90% in untreated patients. Radical surgery combined with chemotherapy for up to 2 years after su...

Nineteen cases of proven hepatic alveolar echinococcosis were examined by magnetic resonance (MR) and the results were compared with CT. Fibrous and parasitic tissue showed low signal both on T1- and, generally, on T2-weighted images. In a few cases a high signal on T2-weighted images may be observed, due either to central necrotic zones or to small peripheral cysts. Central necrosis was more e...

BACKGROUND Human alveolar echinococcosis (AE) is known to be common in certain rural communities in China whilst it is generally rare and sporadic elsewhere. The objective of this study was to provide a first estimate of the global incidence of this disease by country. The second objective was to estimate the global disease burden using age and gender stratified incidences and estimated life ex...