Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that affects the striatum most severely. However, except for juvenile forms, relative preservation of the cerebellum has been reported. The objective of the present study was to perform MRI measurements of caudate, putamen, cerebral, and cerebellar volumes and correlate these findings with the length of the CAG repeat...

BACKGROUND AND PURPOSE We studied six patients suffering from pure, unilateral brain stem infarction to explore the association of remote cerebral and cerebellar blood flow changes with damage at different sites of this region of the brain. METHODS We used single-photon emission computed tomography and [123I]iodoamphetamine to measure regional differences in tracer uptake. Qualitative image a...

This study evaluates the diagnostic value of morphometric magnetic resonance imaging (MRI) in the differential diagnosis among Parkinson's disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). We studied 21 PD cases, 11 MSA-c, 8 MSA-p and 20 PSP cases. Midbrain area (Ams), pons area (Apn), middle cerebellar peduncle (MCP) and superior cerebellar peduncle (SCP) we...

Leucoencephalopathy with neuroaxonal spheroids (LENAS) is a rare disease of cerebral and cerebellar white matter. LENAS usually presents as a disorder of cognition and behaviour, or with gait dysfunction and ataxia. This report describes a patient who had a 14 year course of progressive neurological decline consistent with a clinical diagnosis of probable multiple system atrophy, with prominent...

The term "diaschisis," as originally used by Von-Monakow (1), implies an immediate decrease in neuronal activity in a region due to an interruption of its afferent axonal supply. Experimental studies, in animals , of unilateral ischemia in which neuronal function in the contralateral hemisphere was demonstrated to be impaired, provided evidence for such a mechanism (2). The corpus callosum appe...

Objectives: Cerebellar infarction is an ischemic type episode involving the three main cerebellar arteries. An infarction in each of these arteries causes different but common symptoms, requiring a particularly important contribution of physiotherapy to its treatment. This overview aimed to investigate the effectiveness of physiotherapy programs on the symptoms of patients with cerebellar infar...

ObjectiveWe hypothesize that loss of inhibition from the cerebellum can lead to cortical activation and seizures.BackgroundThe traditional model for development seizures purports source is increased electrical activity originating cerebral neurons. Studies have shown a decrease in results shift hyperexcitable state, which may seizures. Interestingly, 1978 study suggested term “disorder disinhib...

introduction: sexual dimorphisms in biological structures such as brain and behaviour have been widely recognized in animals and humans. the purpose of this study was to examine whether there are sex differences in the size of the cerebellum with other body traits, such as the head, tail and brain. methods: twelve grasscutters comprising of 6 males and 6 females were used in this study. each br...