We made a case-control study to investigate a possible association between ALOX5AP-SG13S114A/T, COX-2-765G/C, and COX-1-50C/T polymorphisms with cerebral infarction in a Chinese population. A total of 411 cases with cerebral infarction were included; 411 controls matched for age, gender, and risk factors were also selected. The ALOX5AP-SG13S114A/T (rs10507391), COX-2-765G/C (rs20417), and COX-1...

BACKGROUND The vascular pathogenesis underlying lobar intracerebral hemorrhage (ICH) is unclear. OBJECTIVE To determine whether certain retinal microvascular signs are associated with lobar ICH to improve understanding of its underlying cerebral vasculopathy. DESIGN Prospective cohort study. SETTING Royal Melbourne Hospital and Westmead Hospital. PATIENTS Of 655 patients with acute stro...

Estrogenic Therapy in Men With Ischemic Cerebrovascular Disease: Effect on Recurrent Cerebral Infarction and Survival • A cooperative clinical investigation was undertaken in 15 Veterans Administration Hospitals to determine whether long-term therapy with conjugated equine estrogens prevented recurrent cerebral infarction or death due to atherosclerotic vascular disease. Follow-up observations ...

Estrogenic Therapy in Men With Ischemic Cerebrovascular Disease: Effect on Recurrent Cerebral Infarction and Survival • A cooperative clinical investigation was undertaken in 15 Veterans Administration Hospitals to determine whether long-term therapy with conjugated equine estrogens prevented recurrent cerebral infarction or death due to atherosclerotic vascular disease. Follow-up observations ...

Estrogenic Therapy in Men With Ischemic Cerebrovascular Disease: Effect on Recurrent Cerebral Infarction and Survival • A cooperative clinical investigation was undertaken in 15 Veterans Administration Hospitals to determine whether long-term therapy with conjugated equine estrogens prevented recurrent cerebral infarction or death due to atherosclerotic vascular disease. Follow-up observations ...

Recent success with thrombolytic therapy for acute myocardial infarction has stimulated interest in its use for stroke. To determine the hemorrhagic potential of thrombolytic therapy in experimental cerebral infarction, we compared a group of tissue plasminogen activator-treated rabbits (n = 4) with 2 groups of streptokinase-treated rabbits (n = 6 in each), as well as with 3 groups of heparin-t...

BACKGROUND AND PURPOSE This study evaluated the characteristics and natural history of patients with lacunar (small, deep) cerebral infarcts in a defined population for comparison of these characteristics to those in patients with nonlacunar infarcts. METHODS This is a population-based study in Rochester, Minnesota, from 1960 to 1984, that used the medical record-linkage system to identify an...

BACKGROUND Recently a new automatic device that measures brachial-ankle pulse wave velocity using an oscillometric method has been developed. However, the practical significance of brachial-ankle pulse wave velocity measurement remains uncertain. The purpose of this study was to examine the association between brachial-ankle pulse wave velocity and symptomatic cerebral infarction in patients wi...