objective: the clinical value of igg anticardiolipin antibody in patients with behçet's disease with or without vascular thrombosis was evaluated.   methods: igg isotype of anticardiolipin (acl) antibody was assessed in 40 behçet's disease (bd) patients with venous or arterial thrombosis, 40 bd patients without venous or arterial thrombosis and 80 healthy subjects as controls. the lev...

A substantial body of evidence supports the hypothesis of a vascular component in the pathogenesis of Alzheimer's disease (AD). Cerebral hypoperfusion and blood-brain barrier dysfunction have been indicated as key elements of this pathway. Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder, frequent in AD, characterized by the accumulation of amyloid-β (Aβ) peptide in cerebral bloo...

in this review the role of cerebrospinal fluid (csf) in mammalian cerebral cortex development has been highlighted. many studies have focused on the potential role of the csf in the developmental process. in particular, the cerebral cortex develops from the germinal epithelium adjacent to the csf. csf contains proteins, growth factors and other neurotrophic factors which are important for neura...

The fetal llama responds to hypoxemia, with a marked peripheral vasoconstriction but, unlike the sheep, with little or no increase in cerebral blood flow. We tested the hypothesis that the role of nitric oxide (NO) may be increased during hypoxemia in this species, to counterbalance a strong vasoconstrictor effect. Ten fetal llamas were operated under general anesthesia. Mean arterial pressure ...

RATIONALE Data from animal models of hypertension indicate that high blood pressure may develop as a vital mechanism to maintain adequate blood flow to the brain. We propose that congenital vascular variants of the posterior cerebral circulation and cerebral hypoperfusion could partially explain the pathogenesis of essential hypertension, which remains enigmatic in 95% of patients. OBJECTIVE ...

Aims: Among the antiepileptic drugs (AEDs) applied for secondary prophylaxis of posttraumatic epilepsy (PTE), carbamazepine (CBZ) may cause severe side effects and worsen traumatic brain injury (TBI). Presentation of Case: Two days after a bicycle accident causing severe TBI, a 23yo female developed a questionable seizure and received CBZ. Since then she required substitution of sodium. Six day...

chapter, particularly in the beginning, assumes a degree of mathematical competence on the part of the reader such that all but the most physically inclined microscopists will be put off. Despite the inate sophistication of most of the topics covered, however, the tone of the contributions is uniformly terse and superficial, thus rendering this volume too pedestrian for specialists. Further, al...

Developmental venous anomaly (DVA)/ Cerebral Venous Angioma is the most common type of cerebral vascular malformations, mostly an incidental benign finding. But there are documented associated complications like parenchymal signal abnormalities, thrombosis, cavernous malformations and atrophy.
 In this report, we present a unique case DVA with cortical changes mimicking Glioma. Altered hae...