BACKGROUND Cervical ripening is an inflammatory reaction. The glucocorticoid receptor (GR) mediates glucocorticoid anti-inflammatory reactions, whereas nuclear factor (NF)kappaB is a key pro-inflammatory transcription factor. Prostaglandins as well as platelet activating factor (PAF) are inflammatory mediators. Inducible nitric oxide synthase (iNOS) regulates the level of nitric oxide (NO) in r...

This study was designed to evaluate the application effect of single balloon catheters and dinoprostone on promoting cervical ripening of pregnant women in late-term pregnancy and their influences on stress and inflammatory responses. A total of 160 pregnant women with indications of labor induction were included and randomly divided into the control (n=80) and observation (n=80) groups. Patien...

The efficacy of intracervical Foley catheter with misoprostol (PGE1) and dinoprostone (PGE2) for preinduction cervical ripening, induction of labour, mode of delivery, induction to delivery interval and maternal complications has been compared.. Women who were admitted to hospital and met criteria for entrance in the trial were counseled and enrolled after informed consent. Inclusion criteria i...

Cervical ripening is as important part of the process of labor induction. While other mechanical methods are available, such as extra-amniotic saline infusion [1] and the use of osmotic dilators and double-balloon catheters, an obstetrical single balloon is commonly used to facilitate ripening of the cervix [2]. It is widely used because it is relatively safe and has few adverse effects. Single...

Introduction: Numerous techniques have been used to ripen the unfavourable cervix to achieve the changes necessary for labour. Prostaglandins are the most commonly used pharmacological agents for ripening of cervix and PGE2 gel is the agent of choice for this purpose. Materials and methods: In present study 100 singleton pregnant women who were counselled & in whom cervical ripening and labour ...

At times, despite an unripe cervix, induction of labor may be needed. In these cases, a safe and suitable method should be considered for cervical ripening and pregnancy termination. The aim of this study is the comparison of vaginal misoprostol with Foley catheter for cervical ripening and induction of labor. This randomized clinical trial was performed on 108 pregnant women who had referred t...