S100A7 is an EF-hand calcium-binding protein that has been suggested to be implicated in cell proliferation, migration, invasion and tumor metastasis. However, its role in cervical cancer has not yet been fully clarified. The present study used immunohistochemistry analysis of S100A7 in clinical specimens of cervical cancer to show that S100A7 expression was significantly upregulated in cervica...

Hibernomas are uncommon benign soft tissue tumours mimicking brown fat. They are mostly seen in the fourth and fifth decades of life. Only few cases in the cervical area have been reported. Because of its rarity in pediatrics and difficult diagnosis, we report a tow year-old patient with a cervical tumor. Ultrasound and computed tomography exams showed an infiltrative, with hypervascular and li...

Background: Cervical myelopathy is commonly seen in the older population caused by a degenerative process, but rare case, it can be pediatric due to uncommon causes, such as an intraspinal cyst. This case report aims discuss of cervical endodermal cyst two-year-old child.Case Presentation: A 2-year-old child with limited neck movement and abnormal body posture from 6 months before admission hos...

Cervical carcinoma is the second most prevalent malignancy in females worldwide. The crucial etiologic factors involved in the development of cervical carcinoma include infection with papillomavirus, and the structural or functional mutation of oncogenes and tumor suppressor genes. The abnormal change of octamer transcription factor 1 (OCT1) is associated with tumor progression and a poor patie...

the previous studies reported some information about prevalence release of high-risk hpv types in hsil or cervical cancer globally and in iran, however, this information is not enough for final judgment about vaccination against hpv or any screening program. the aim of the present study was to assess the hpv type distribution in hsil and icc specimens of women attending shahid beheshti universi...

Cervical cancer is the third most common cancer in females worldwide. The treatment options for advanced cervical cancer are limited, leading to high mortality. Ezrin is a membrane-cytoskeleton-binding protein recently reported to act as a tumor promoter, and we previously indicated that the aberrant localization and overexpression of Ezrin could be an independent effective biomarker for progno...

Tumor-associated macrophages (TAMs) are important components in tumor microenvironment. This study intended to explore the influence of TAMs on cervical cancer cells proliferation and migration. The expression levels markers, CD68 CD163, tissues were examined by immunohistochemistry increased with progression lesions (p < 0.05). M2-like phenotype (PMA(Polymethacrylate) induced THP-1 cells) noti...

Background and Aim: Generally, in patients with cervical cancer, careful preliminary evaluation is necessary for avoiding improper surgical procedures and making effective clinical decisions for treatment. The aim of this study was to determine surgeons’ errors, which necessitate a combination of surgery and radiotherapy for cervical cancer patients.    Methods: In this retrospective study, med...

Hysteroscopic complications are infrequent. Major complications include: 1. Uterine perforation that is the most common complication of operative hysteroscopy (0.8 - 1.6 %). The perforation rate is less during diagnostic hysteroscopy. 2. Bowel or bladder injury which is rare, but may occur in association with uterine perforation or as a result of use of electrical current. 3. Cervical laceratio...