Carcinomas of the uterine fundus occur more frequently among women showing unusual production of estrogenic hormone than in normal women (15). Although there is less evidence of a correlation of abnormal production of estrogens and tumors of the uterine cervix, at least one investigator has reported that deficiencies of vitamins, with possible coincident impairment of estrogen inactivation, was...

The intrauterine device (IUD) is the most widely used reversible forms of contraception in the world [1]. Given its excellent efficacy and long-acting properties, IUD remains the most simple, cost-effective contraceptive method that is widely used in China. Ideally, the IUD should be removed soon after the menopause, however, many women with an IUD fail to remove it following the menopause for ...

Profound changes occur in the uterine cervix during pregnancy. In particular, the extracellular matrix of the connective tissue is remodelled extensively. To elucidate the mechanisms involved in this process, we have analysed the proteoglycan pattern in the human cervix from pregnant and non-pregnant women. Proteoglycans of the cervix tissue specimen were extracted with 4 M guanidine hydrochlor...

Utero cervix usually constitutes the majority of specimens received at histopathology section in department of pathology. A variety of rare but interesting lesions may occur in the cervix and create problems in diagnosis. Difficulties in distinction from well-differentiated adenocarcinoma can result in potentially major adverse consequences for the patient in the form of inappropriate therapy. ...

OBJECTIVES This investigation examined human papillomavirus (HPV) in pregnant women in order to characterize viral prevalence, types and concordance between infection in the cervix and in the oral cavity. METHODS A total of 577 pregnant women seeking routine obstetric care were evaluated for HPV infection in their cervix during gestation and immediately before delivery, and in the oral cavity...

The present study was designed to determine the effect of the spatial gradient from the cervix to the uterine fundus on the control of local prostaglandin H synthase (PGHS) 2 mRNA expression. We performed total cesarean hysterectomies during the last trimester in 12 pregnant baboons, 7 not in labor and 5 in labor, and examined PGHS2 mRNA expression throughout the uterus. PGHS2 mRNA abundance wa...

Cervicography is a technique for visual screening of uterine cervix images for cervical cancer. One of our research goals is the automated detection in these images of acetowhite (AW) lesions, which are sometimes correlated with cervical cancer. These lesions are characterized by the whitening of regions along the squamocolumnar junction on the cervix when treated with 5% acetic acid. Image pre...

OBJECTIVES Carcinoma of the cervix is the most common cause of the death in Nepal. Cervical carcinoma does not develop suddenly from normal epithelium but is presented by a spectrum of intraepithelial neoplastic changes that are precancerous lesion and were termed as cervical intraepithelial neoplasia (CIN). Cervical cytological screening is designed to detect over 90% of cytological abnormalit...

Objectives: The study aims to investigate the efficacy of screening by low-cost technology in down-staging and reduction of mortality due to breast and cervix cancer. Methods: The present trial is a community-based, cluster randomised controlled cohort study on screening for breast and cervix cancers (clinical breast examination and visual inspection of the cervix after application of 4% acetic...