Basic and clinical studies on mechanobiology of cells and tissues point to the importance of mechanical forces in the process of skin regeneration and wound healing. These studies result in the development of new therapies that use mechanical force which supports effective healing. A better understanding of mechanobiology will make it possible to develop biomaterials with appropriate physical a...

The liver has an exceptional replicative capacity following partial hepatectomy or chemical injuries. Cellular proliferation requires increased production of energy and essential metabolites, which critically depend on the mitochondria. To determine whether Top1mt, the vertebrate mitochondrial topoisomerase, is involved in this process, we studied liver regeneration after carbon tetrachloride (...

The ciliate protozoan, Stentor coeruleus, has been a favored organism in which to investigate nucleo-cytoplasmic relationships during intracellular regeneration and reorganiza tion. The morphology of stentors and the changes that occur during regeneration and division have been described in detail and were reviewed in Tartar's (1961) treatise. Studies of either regenerative or replicative morph...

Liver cell growth can be induced in two distinct patterns: compensatory regeneration and direct hyperplasia. In the former, DNA synthesis is preceded by a loss of liver cells such as seen after partial resection of the liver or cell necrosis, whereas in direct hyperplasia, DNA synthesis is stimulated without cell loss. During the past decade, considerable advances have been made in understandin...

Abstract In tissue engineering, bioactive materials play an important role, providing structural support, cell regulation and establishing a suitable microenvironment to promote regeneration. As the main component of extracellular matrix, collagen is natural material it has been widely used in scientific research clinical applications. Collagen available from wide range animal origin, can be pr...

Periodontal regeneration has been challenged with chemical reagents and/or biological approaches, however, there is still no sufficient technique that can regenerate complete periodontium, including alveolar bone, cementum, and well-oriented collagen fibers. The purpose of this study was to examine multi-layered sheets of periodontal ligament (PDL)-derived cells for periodontal regeneration. Ca...

Virtually all types of periodontal disease are caused by periodontal pocket infections, although several other factors, including trauma, aging, systemic diseases, genetics, etc., can contribute to the destruction of the periodontium (1, 18, 31, 52, 60, 107, 128, 127, 194). Repair of the periodontium and the regeneration of periodontal tissues remains a major goal in the treatment of periodonta...

Freshwater planarians have remarkable regeneration ability. We did the elementary experiment which utilized the regeneration capacity of this planarian for safety evaluation of chemicals. The regeneration level of planarian measured the regeneration rate from the tail side where the reproduction of eyes was able to watch. This time, we examined the regeneration inhibition of the planarian by th...

Porous materials with photochromic units are currently under investigation as light allows for environmentally friendly and highly energy-efficient control gas separation storage, chemical sensing, drug delivery. In the application of photo-switching to CO 2 capture, researchers have tried endow a diversity porous such metal-organic frameworks organic polymers photo-responsive units. This revie...

In this work an experimental proof-of-concept of the Ca-Cu process has been carried out. The combines sorption-enhanced steam reforming methane with a Ca-based sorbent chemical looping Cu-based oxygen carrier to provide energy for regeneration. Each step studied separately different operating pressures and inlet gas compositions, addition complete cycles (including all three consecutive steps, ...