To date, most research on freshwater cyanotoxin(s) has focused on understanding the dynamics of toxin production and decomposition, as well as evaluating the environmental conditions that trigger toxin production, all with the objective of informing management strategies and options for risk reduction. Comparatively few research studies have considered how this information can be used to unders...

Formaldehyde treatment is a method routinely used to detoxify diphtheria, tetanus, and pertussis toxins as well as other molecules suitable for vaccine production. To investigate whether chemical detoxification alters the immunological properties of vaccine components, we have treated the pertussis toxin mutant PT-9K/129G with formaldehyde and tested the properties of the resulting molecules. V...

background: this cross sectional study was conducted to evaluate the effect of &gamma-rays; and electron-beam irradiation with a commercial toxin binder-milbond-tx on the performance, feed components, and meat quality of japanese quails challenged with aflatoxin b1. methods: overall, 168 one-d-old chicks (japanese quails) were allocated to eight treatments with three replicates based on a compl...

abstract how to cite this article: eryılmaz a, başal y, günel c, ozkul a, tosun a. successful treatment of essential palatal tremor lasting over a long term with a rare application of botulinum toxin in a child. iran j child neurol. autumn 2015;9(4): 75-77. abstract objective attention deficit hyperactivity disorder (adhd) is one of the most prevalent mental health disorders. in recent years, t...

purpose : recession is the main surgical procedure in correction of eye deviation in duane’s syndrome. we evaluate the efficacy of botulinum toxin injection in the treatment of this type of strabismus instead of surgery or before it. methods : three patients with duane’s syndrome type i and one patient with type ii were selected at poostchi eye clinic from patients who diagnosed primarily and h...

Recombinant baculovirus expressing insect-selective neurotoxins derived from venomous animals are considered as an attractive alternative to chemical insecticides for efficient insect control agents. Recently we identified and characterized a novel lepidopteran-selective toxin, Buthus tamulus insect-selective toxin (ButaIT), having 37 amino acids and eight half cysteine residues from the venom ...

Recent aggressive attacks on innocent citizens have resulted in governments increasing security. However, there is a good case for prevention rather than reaction. Bioweapons, mycotoxins, fungal biocontrol agents (FBCA), and even pharmaceuticals contain, or are, toxins and need to be considered in the context of the new paradigm. Is it desirable to discuss such issues? None of the fungi are (a)...

Symptoms consistent with inhalation toxicity have long been associated with Florida red tides, and various causal agents have been proposed. Research since 1981 has centered on a group of naturally occurring trans-fused cyclic polyether compounds called brevetoxins that are produced by a marine dinoflagellate known as Karenia brevis. Numerous individual brevetoxins have been identified from cul...

One has but to know something of the precarious character of routine toxin production to be aware that the artificial conversion of low value toxins to those of high titre is a problem of more than mere academic interest. In the search for a suitable process by which this may be done it is soon realised that purely chemical methods such as those referred to so completely by Pick [1912] are not ...

Polypeptide neurotoxins from sea anemones have been useful biological probes for sodium channel function. Cationic residues, specifically Arg-14, which is conserved in essentially all known sea anemone toxins, have been generally thought to be important determinants of their binding affinity and/or efficacy. In the present study, we have constructed site-directed mutants of the Anthopleura xant...