Chemically modified aptamers have recently emerged as important materials for nucleic acid based therapeutics and diagnostic tools. Here, we report in vitro evolution of azobenzene-modified DNA by capillary electrophoresis (CE)-SELEX method. Azobenzene has been considered to be a fascinating functional group due its trans–cis photo-isomerization property. We harnessed C5-azobenzene-modified 2?-...