BACKGROUND In contrast with established evidence linking high doses of ionizing radiation with childhood cancer, research on low-dose ionizing radiation and childhood cancer has produced inconsistent results. OBJECTIVE We investigated the association between domestic radon exposure and childhood cancers, particularly leukemia and central nervous system (CNS) tumors. METHODS We conducted a n...

Over 8,500 children under age 15 years are diagnosed with cancer each year in the United States (1). Unlike adults, where epithelial tumors predominate, the most common types of cancer in children include the leukemias and lymphomas and the tumors of the central and sympathetic nervous systems, soft tissue, bone, and kidney. The overall incidence rate for childhood cancers has increased signifi...

BACKGROUND An increasing percentage of childhood cancer patients are surviving their disease, but there is limited research on late recurrence. We sought to estimate late recurrence rates for the most common pediatric cancers and to determine risk factors for late recurrence. METHODS The incidence of late recurrences, or first recurrences that occurred more than 5 years after diagnosis, was a...

Introduction: Childhood cancer is a small proportion of all cancers but still major public health problem. Objective: To describe the 5-year incidence and mortality rates net survival childhood in Uruguay. Method: Data on malignant tumors diagnosed children aged 0-14 were included for period 2011-2015, obtained from National Pediatric Registry Cancer Ministry Health Mortality Registry, classifi...

INTRODUCTION The aim of this study was to assess cancer incidence in childhood-onset systemic lupus erythematosus (SLE). METHODS We ascertained cancers within SLE registries at 10 pediatric centers. Subjects were linked to cancer registries for the observational interval, spanning 1974 to 2009. The ratio of observed to expected cancers represents the standardized incidence ratio (SIR) or rela...

Background                                               Pediatric acute lymphoblastic leukemia (ALL) is the most common, yet curable childhood malignancy within the pediatric cancers; but in most developed and developing countries cost of cancer treatment in children with ALL is high. So, we specified the range of expenses for the treatment of pediatric cancer and compared the results in devel...

Cancer is one of the major causes of morbidity and mortality across the world but more in developing countries. Worldwide about 160,000 new cases and 90,000 deaths occur every year in children under the age of 15 years due to cancer. Childhood cancer is the second leading cause of death worldwide surpassed only by accidents (1). Data on cancer incidence are scanty in developing countries. Most ...