Chitosan has been extracted from different marine crustacean from the Black Sea of Bulgarian Gulf. The contents of the various exoskeletons have been analyzed and the percent of the inorganic salt , protein, chitinand chitosan was determined. Deacetylation of the different chitin produced was conducted by the conventional thermal heating method. The chitosan was characterized by elemental analy...

In this paper, the effect of chitosan molecular weight on the characteristics (size, encapsulation efficiency, zeta potential, surface morphology and release rate) of vitamin C encapsulated tripolyphosphate cross-linked chitosan (TPP-chitosan) microspheres. The molecular weight of chitosan had a noticeable influence on the size, encapsulation efficiency, zeta potential, surface morphology and c...

BACKGROUND: The development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. Recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-GP) solutions due to their good biodegradability and thermosensitivity. OBJECTIVES: The general aim of this study was to prepare a novel in si...

Natural and biodegradable chitosan with unique amino groups has found widespread applications in tissue engineering and drug delivery. However, its applications have been limited by the poor solubility of native chitosan in neutral pH solution, which subsequently fails to achieve cell-laden hydrogel at physiological pH. To address this, we incorporated UV crosslinking ability in chitosan, allow...

Multiple pH-sensitive composites have been prepared through non-covalently functionalizing chemically converted graphene (CCG) with chitosan. Chtiosan exhibits as polybases and CCG shows characteristics of polyacids. Owing to the synergistic effects of chitosan and CCG, chitosan decorated graphene (CS-G) presents a multiple pH-responsive behavior that it can be dispersed well whether in acidic ...

A thermosensitive polymer can be held liquid before being injected to deliver living cells or therapeutic agents and formed monolithic gels when injected in vivo. In this study, chitosan-based thermosensitive hydrogels were prepared, characterized and the biocompatibility for culturing mice bone mesenchymal stem cells (BMSC) on 2D films and within 3D hydrogel were investigated. The gelation tem...

Cellulose/chitosan homogeneous solutions were prepared in 1-ethyl-3methylimidazolium acetate ([EMIM]Ac) ionic liquid. Steady and oscillatory dynamic rheological properties were studied with a Haake Mars-ΙΙΙ rotational rheometer. Rheological results show that cellulose/chitosan [EMIM]Ac solutions are a pseudoplastic liquid, and the viscosity of the solution decreases with increasing of chitosan ...

This study was developed with the purpose to investigate the effect of polysaccharide/plasticiser concentration on the microstructure and molecular dynamics of polymeric film systems, using transmission electron microscope imaging (TEM) and nuclear magnetic resonance (NMR) techniques. Experiments were carried out in chitosan/glycerol films prepared with solutions of different composition. The f...

Chitosan can readily dissolve in a precooled aqueous alkali-urea solution, a solvent that has previously been developed to dissolve cellulose. Upon heating, the resulting solutions quickly become a gel. The thermal gelling of the chitosan solutions was studied by rheology. Initially, a temperature ramp test was used to determine the gelation temperatures (Tgel). It was found that Tgel does not ...

Ni–Ti shape memory alloys (Nitinol) are suitable for biomedical applications such as orthodontic, orthopedic, and cardiovascular implants. However, to avoid local inflammatory processes, efforts being made functionalize the surface of alloy with bioactive materials. Chitosan-based composite coatings can be applied improve properties due their excellent properties, low toxicity, biocompatibility...