Translocations are being increasingly proposed as a way of conserving biodiversity, particularly in the management of threatened and keystone species, with the aims of maintaining biodiversity and ecosystem function under the combined pressures of habitat fragmentation and climate change. Evolutionary genetic considerations should be an important part of translocation strategies, but there is o...

Translocation of the mRNA-tRNA complex in the ribosome, which is catalyzed by elongation factor EF-G, is one of critical steps in the elongation cycle of protein synthesis. Besides this conventional forward translocation, the backward translocation can also occur, which can be catalyzed by elongation factor LepA. However, the molecular mechanism of the translocation remains elusive. To understa...

Translocations between the two large autosomes were scored in the progeny of males that had been fed mitomycin-C. The frequencies were the same in spermatogonia sampled after 12 and 25 days and in spermatozoa stored for the same periods in untreated females.

In this article, we show that introns harboring translocation breakpoints in tumors are significantly longer than non-translocated introns of the same genes but are not enriched significantly in sequence elements potentially involved in chromosomal rearrangements. Our findings provide evidence that double-strand breaks, the type of DNA damage that leads to translocations in tumors, are created ...

A potential-controlled two-step bidirectional communication protocol between the nanoswitches [Cu(1)](+), 2 and 3 is set up, in which ligand followed by metal-ion oxidation drives two subsequent metal ion translocations (self-sorting) changing the switching state at each switch. The communication is reset to its starting point by a two-electron reduction.

A couple was referred for cytogenetic examination due to idiopathic miscarriages. The proband proved to be a carrier of chromosomal translocation and her partner's karyotype was found to be normal. The karyotype of the proband is 46,XX,t(4;22)(q23;q11.2) and can be regarded as a reason of fertility problems in the investigated couple. The risk of further miscarriages is high, but the risk of a ...

Alarm over the prospects for survival of species in a rapidly changing world has encouraged discussion of translocation conservation strategies that move beyond the focus of 'at-risk' species. These approaches consider larger spatial and temporal scales than customary, with the aim of recreating functioning ecosystems through a combination of large-scale ecological restoration and species intro...

ETEROZYGOUS autosomal translocations have been shown to affect recomHbination in the X chromosome in various ways (HINTON 1965); translocations with long interstitial distances increased recombination in X, those with short interstitial distances decreased recombination in X, and those with intermediate interstitial distances had little or no effect. Other incidental tests of translocation hete...

In outsourcing, management seeks to achieve costs savings, operational efficiency, customer satisfaction, and/or company growth. We integrate the ANP with the perspectives in Balanced Scorecard (BSC) for IT outsourcing decision making. The proposed BSC-ANP model helps evaluate the impact of decision on firm performance and confirms the existence of indicator interactions.