background : according to the literature, there are a number of chronic and acute myeloid leukemias with unique, complex chromosome translocations. this study aims to conduct a brief review of the incidence of complex chromosome translocations in myeloid leukemia and reports a case of myeloid leukemia with complex chromosome translocations. methods :we conducted a web-based search for all peer ...

background: chromosome abnormality (ca) including sex chromosomes abnormality (scas) is one of the most important causes of disordered sexual development and infertility. scas formed by numerical or structural alteration in x and y chromosomes, are the most frequently ca encountered at both prenatal diagnosis and at birth. objective: this study describes cytogenetic findings of cases suspected ...

down syndrome is one of the most common causes of mental retardation observed in approximately 1/700 live birth. the use of two or more str markers related to chromosome 21 facilitates the diagnosis of down syndrome within about six hours from the collection of the samples. this is the first study has been performed in iranian population to assess the diagnostic value of using small tandem repe...

Mice derived entirely from embryonic stem (ES) cells can be generated through tetraploid complementation. Although XY male ES cell lines are commonly used in this system, occasionally, monosomic XO female mice produced spontaneous Y chromosome loss. Here, we describe an efficient method to obtain by CRISPR-Cas9-mediated deletion of the chromosome, allowing generation clonal The viable and able ...

47XYY syndrome is a rare sex chromosome variant with an extra Y chromosome. Most patients karyotype have normal phenotype. This disorder seems to be associated higher risk of developing behavior and cognitive problems, tall stature infertility in adulthood. We report here case 47, XYY 11-beta-hydroxylase deficiency revealed by advance along precocious puberty after obtaining informed consent fr...

Chromosome numbers of one species Eranthemum (E. macrophyllum Wall. ex Nees) and five Strobilanthes [S. affinis (Griff.) Terao J. R. I. Wood et Benett., S. biocullata Y. F. Deng & Wood, dimorphotricha Hance, heteroclita D. Fang H. Lo pseudocollina K. He Qin] in the family Acanthaceae from China have been reported for first time. The chromosome were determined as 2n=4x=44 E. macrophyllum, 2n=2x=...

Detection of Selection Signatures on the X Chromosome in Iranian Dromedary Camels using Whole Genome Sequencing Data

Chromosome number is a central feature of eukaryote genomes. Deciphering patterns chromosome-number change along phylogeny to the inference whole genome duplications and ancestral chromosome numbers. ChromEvol probabilistic tool that allows evaluation several models evolution their fit data. However, fitting model does not necessarily mean describes empirical data adequately. This vulnerability...