Although an understanding of the phenotypic similarities and differences between individuals trisomic and tetrasomic for the same chromosome or chromosome segment is of considerable theoretical interest with regard to the relationship of the phenotypic features of aneuploid states to changes in the dosage of specific genes, the data obtainable from human cases of tetrasomy do not permit firm co...

BACKGROUND Acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas are associated with the B-cell chromosomal translocation t(8;14)(q24; q32). The most common secondary chromosome aberrations in these patients involve 1q and are believed to be associated with tumor progression. A mechanism for the origin of these 1q aberrations has not been demonstrated. To their knowledge, the autho...

We investigated whether nicotine exposure in vitro of mouse oocytes affects spindle and chromosome function during meiotic maturation (M-I and M-II). Oocytes in germinal vesicle (GV) stage were cultured in nicotine for 8 h or for 16 h, to assess effects in M-I and in metaphase II (M-II). The latter culture setting used the three protocols: 8 h nicotine then 8 h medium (8N + 8M); 16 h nicotine (...

The current study was conducted to identify the quantitative trait locus (QTL) for the body weight at age 1, 7, 14, 21 and 28 days and daily gain at age 0-1, 1-2, 2-3 and 3-4 weeks, slighter carcass weight and tonic immobility in Japanese quail. Two divergently lines of wild and white Japanese quail which maintained in the Animal Science Research Center of the Shahid Bahonar University of Kerma...

Background: To improve the detection rate of chromosome abnormalities in fetuses and to reduce birth defects elderly pregnant women using karyotype analysis combined with microarray (CMA) technique. Methods: Overall, 210 singleton pregnancies aged between 16 30 weeks (mean gestational age, 19.19 weeks) 35 47 years 38.08 years) were selected from January 1, 2020 June 2021 Eugenics Genetics Depar...

Chromosome number and karyotype of Astragalus stereocalyx Bornm. (Milk-vetch) in the section Stereocalyx Bornm. distributing naturally in Turkey were analyzed in detail. This species is endemic to Turkey and growing in Eskişehir and Konya provinces. Squash preparation method was used for chromosome study in this species. The somatic chromosome number was determined as 2n = 16 in A. stereocalyx....

We report on two patients who developed a secondary acute myeloid leukemia (sAL) after treatment for non-Hodgkin's lymphoma (NHL) with regimens containing low to intermediate doses of VP16. Clinical and hematologic features in these two patients were consistent with epipodophyllotoxin-associated sAL. In one case, a rearrangement of chromosome band 11q23 was detected.

This report describes two patients with a distinctive type of dicentric autosomal chromosome formed by breakage and union between homologous chromosomes. These stable chromosomes possess two C bands, implying the presence of two centromeric regions. The first child, evaluated for dysmorphic features was shown to have an abnormal chromosome 16, designated as 46, XX, -16, + dic (16) (pter leads t...

An enzymatic maceration and Giemsa staining method was used to compare the karyotypes of Crotalaria laburnifolia (trifoliate) C. spectabilis (simple leaves) species belonging distinct morphological sections with different degrees floral specialization. Both taxa share a 2n=16, asymmetric chromosome complement, relatively similar karyotypic formulae. However, differences in chromosome-SAT, sizes...