概 要 慢性 気管支 炎に検 出 され る リウマチ 因子(RF)と 本症 の二,二 臨床所見 との比較検 討を行 な うと ともに,こ れ と比較す る意味 で他の慢性肺 疾患に ついて も併せ検 討 した.そ の結果,RFの 頻度 は慢性気 管支炎 において最 も高 く,つ いで サル コイ ドーシス,塵 肺,気 管支端 息お よび肺結 核の順で あつた.慢 性気管 支炎を 西本分類 でみた場合 は感染を主症 状 とす る感染閉塞型 お よび感染型 に,ま た 換 気機能 に よる分 類では 閉塞型お よび混合型 にそれぞれRF陽 性者 を多数認め た.喀 疾の性 状を粘液 性 お よび膿 性 に分 け る と膿性 痰 を示 す症例 にRFは 高頻度 であ り,肺機 能検査 では%DLCOお よびstatic complianceの 低下 した ものにやや高 率に出現す る傾向 ...

Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481 Management strategy . . . . . . . . . . . . . . . . . . . . 481 The epidemiology of chronic chough . . . . . . . . . . . . 482 Chronic cough in adults . . . . . . . . . . . . . . . . . . 482 Chronic cough in childhood . . . . . . . . . . . . . . . 482 Clinical history and examination of the patient with chronic cough . . ....

Ambroxol is a mucolytic agent which is widely used in chronic bronchitis in Europe. We conducted a double-blind randomized controlled trial of ambroxol vs matched placebo in 90 patients with chronic bronchitis and difficulty clearing secretions. It was concluded that there was no advantage to taking ambroxol.

BACKGROUND A study was undertaken to evaluate Chlamydia pneumoniae chronic infection, other respiratory infections, and functional impairment in patients with chronic bronchitis (stage 1) and to examine chronic C pneumoniae infection, rate of acute exacerbations of chronic bronchitis, and rate of C pneumoniae eradication following antibiotic treatment (stage 2). METHODS In the stage 1 study r...

Pulmonary emphysema is a chronic disease defined pathologically as an abnormal permanent destruction and enlargement of air spaces distal to the terminal bronchioles, accompanied by the destruction of alveolar walls without predominant fibrosis. Emphysema frequently occurs in overlapping association with chronic bronchitis which is clinically defined as chronic productive cough for three months...

BACKGROUND Chronic bronchitis causes high morbidity and mortality throughout the world. It is basically a preventable disease. However, few population based studies of chronic bronchitis have been carried out in less developed countries. METHODS A population based cross sectional survey was conducted to determine the prevalence of chronic bronchitis and associated risk factors in an urban are...

OBJECTIVES Nonasthmatic eosinophilic bronchitis is a newly recognized cause of chronic cough. Our objective was to review the pathogenesis, natural history, diagnosis, and treatment of this condition. METHODS The current literature was reviewed using an Ovid MEDLINE and PubMed literature review for all studies published in the English language from 1963 to December 2004 using the medical subj...

The chronic obstructive pulmonary disease (COPD) encompasses two phenotypically related diseases, chronic bronchitis and emphysema [1-2]. Although the hallmark of COPD is inflammation and inability to maintain efficient gas exchange, emphysema is often characterized by atypical over-distension of the alveoli and permanent destruction of the surrounding supporting structures leading to irreversi...