Primary liver cancer occurs mainly as a result of chronic liver disorders due to hepatitis virus infection. The important thing in preventing liver cancer is to prevent hepatitis virus infection and eliminate hepatitis virus in chronic hepatitis patients. In order to eliminate hepatitis virus in chronic viral hepatitis, therapies with interferon or recently introduced lamivudine are indicated f...

Hepatitis B viruses specifically target the liver, where they efficiently infect quiescent hepatocytes. Here we show that human and avian hepatitis B viruses can be converted into vectors for liver-directed gene transfer. These vectors allow hepatocyte-specific expression of a green fluorescent protein in vitro and in vivo. Moreover, when used to transduce a type I interferon gene, expression o...

background: with respect to the importance of hepatitis a in patients with chronic liver disease, current study was conducted with the aim of determining the prevalence of previous hepatitis a infection in hepatitis b virus carriers with different stages of liver disease. materials and methods: this was a cross sectional study. 283 hbsag positive subjects (including 118 inactive carriers, 144 p...

OBJECTIVE To determine the duration of protection from hepatitis B vaccine given in infancy and early childhood. DESIGN Cross sectional serological study of hepatitis B virus infection in children of various ages 14 years after the start of a trial of vaccination regimens. SETTING Two villages in the Gambia. PARTICIPANTS Children and adolescents given hepatitis B vaccine in infancy or ear...

Since the discovery of the hepatitis B virus (HBV) by Blumberg et al., nearly half a century ago, the subsequent development of a vaccine, understanding of the patho‐ genesis, and the advent of antiviral drugs, the prevalence of chronic hepatitis B has decreased from approximately 5% to 3.61% of the worldwide population. Despite this improvement, approximately 248 million individuals are still ...

INTRODUCTION Five nucleos(t)ide analogs are used to treat chronic hepatitis B. Ideal nucleos(t)ide analog therapy in chronic hepatitis B patients with kidney transplantation must ensure virological suppression and minimize renal injury. However, resistance to nucleos(t)ide analogs frequently results in virological breakthrough, hepatitis flare, and complicated deterioration of the transplanted ...

BACKGROUND Hepatitis B virus (HBV) has been reported as a coinfection with hepatitis C virus (HCV), hepatitis D virus (HDV), cytomegalovirus (CMV), and human immunodeficiency virus (HIV). CASE REPORT A 34-year-old female presented to our clinic with epigastric pain and severe acute hepatitis manifested as jaundice associated with hyperbilirubinemia, elevated transaminases, and coagulopathy. The...

Psychosocial issues and the quality of life are important components at the patients diagnosed with chronic hepatitis B and C. In function of the severity of the infection with virus B or the patients who already have cirrhosis, the treatment and psychosocial education should be improved because they have bigger problems. The frequency of psychosocial disorders seems to be raised at the patient...

Many recent and significant advances in the field of chronic viral hepatitis, including therapy, suggest that an update on chronic hepatitis is timely. Chronic hepatitis B virus infection remains a significant worldwide cause of liver cirrhosis and hepatocellular carcinoma, despite the wide availability of a long established and effective vaccine. Transmission occurs via perinatal, sexual, and ...