Serhan and colleagues introduced the term "Resoleomics" in 1996 as the process of inflammation resolution. The major discovery of Serhan's work is that onset to conclusion of an inflammation is a controlled process of the immune system (IS) and not simply the consequence of an extinguished or "exhausted" immune reaction. Resoleomics can be considered as the evolutionary mechanism of restoring h...

Not only bile but also chronic cholecystitis may play a role in gallbladder carcinogenesis. Numerous studies have revealed a close correlation between chronic inflammation and neoplasia. The experiments were conducted on paraffin sections, obtained from 377 surgically resected gallbladders with chronic cholecystitis. Immunohistochemical reaction was conducted on deparaffinized sections, using a...

Inflammation in the middle ear mucosa, which can be provoked by different primary factors such as bacterial and viral infection, local allergic reactions and reflux, is the crucial event in the pathogenesis of otitis media with effusion (OME). Unresolved acute inflammatory responses or defective immunoregulation of middle inflammation can promote chronic inflammatory processes and stimulate the...

Multiple risk factors are known to exist that will attack cells at various parts of the body eliciting new inflammation sites hence new inflammatory diseases. Acute inflammation usually takes place first in response to the attack of the risk factor (s). As soon as the risk factor (s) is removed, the acute inflammatory response will stop. Conceivably, acute inflammation does not lead to oxidativ...

Chronic kidney disease (CKD), also known as renal failure, primarily affects people with a history of hypertension and diabetes. In this medical condition, the rate filtration or function can decrease over course month year. Several studies have found an increase in pro-inflammatory cytokines patients CKD. Platelet dysfunction hyperreactivity been linked to chronic inflammation. When platelet c...

Obesity is the accumulation of abnormal or excessive fat which leads to inflammation and disturbs optimal state health an individual. development both cardiovascular diseases non-cardiovascular such as psoriasis, depression, cancer, renal etc. If level adiponectin decreased, a significant predictor mortality, associated with impaired fasting glucose, leading type-2 diabetes development, metabol...

Chronic inflammation is a significant concern due to its association with various pathological conditions. As result, extensive research has been conducted identify new natural products that can effectively treat acute inflammation, which the potential inhibit chronic inflammation. In our study, we aimed Indonesian medicinal plants ability proinflammatory agents, specifically targeting NF-κB, c...

Chronic bronchitis is a clinical syndrome, defined on the basis of sputum production [1, 2]. Investigations have demonstrated that airway inflammation is central to the clinical changes associated with chronic bronchitis. Histological investigations of surgical and autopsy specimens have provided material to determine the site and nature of the airway inflammation. Sampling of the airways via f...

The human gastrointestinal tract is occupied by a complex and abundant microbial community reaching as high as 10 13 –10 14 microorganisms in the colon. This micro-biota participates in a symbiotic relationship with their eukaryotic host, and this partnership is viewed as essential for maintaining homeostasis. The microbiome contains a wealth of information, encompassing 150-fold as many genes ...

Introduction Inflammation is characterized by the infiltration of plasma and leukocytes to tissues that undergo disrupted homeostasis [1]. The causes of inflammation range from pathogenic infection, tissue injury to tissue stress and malfunction [1]. Inflammatory process is critical for normal physiological responses against infection and tissue damage, and promotes the clearance of invading pa...