Freshwater systems are at risk owing to increasing carbon dioxide (CO2) levels, and one of the possible reasons for these elevations is the deployment of non-physical fish barriers to prevent invasive fish movements. Carbon dioxide barriers have the potential to create short, chronic and intermittent exposures of CO2 for surrounding freshwater biota. Although intermittent exposures to a stresso...

Background: Obstructive sleep apnea syndrome (OSAS) is characterized by chronic intermittent episodes of upper-airway obstruction with hypoxia and is associated with increased risk of cardiovascular diseases, including myocardial hypertrophy. Chronic intermittent hypoxia (CIH) has been shown to induce apoptosis in cardiomyocytes. However, the mechanisms of cardiomyocytes apoptosis under CIH lar...

AIMS Delayed lipoprotein clearance is associated with atherosclerosis. This study examined whether chronic intermittent hypoxia (CIH), a hallmark of obstructive sleep apnoea (OSA), can lead to hyperlipidaemia by inhibiting clearance of triglyceride rich lipoproteins (TRLP). METHODS AND RESULTS Male C57BL/6J mice on high-cholesterol diet were exposed to 4 weeks of CIH or chronic intermittent a...

Alcohol exposure induces multiple neuroadaptive changes in the CNS that can have serious long-term consequences on CNS function including cognitive effects and attenuation of learning and memory. The cellular mechanisms underlying the CNS effects of alcohol have yet to be fully elucidated and are likely to depend on the pattern and dose of alcohol exposure. Using electrophysiological recordings...