The mortality rate of chronic obstructive pulmonary disease (COPD) patients with community-acquired pneumonia (CAP) is reported to be low. However, studies carried out to date have included <20% of critically ill patients. The current authors performed a secondary analysis of a prospective study evaluating 428 immunocompetent patients admitted to the intensive care unit (ICU) for severe CAP. In...

Background: One of the genetic risk factors for chronic obstructive pulmonary disease (COPD) is deficiency of Alpha-1 Antitrypsin (A1AT). There is no exact statistics about the prevalence of this disease in different regions of Iran. The present study aimed to determine the prevalence of alpha-1 antitrypsin (A1AT) deficiency in COPD patients in Kerman, Iran. Metho...

Background- Chronic Obstructive Pulmonary disease (COPD) as defined by Global Initiative for Lung Disease (GOLD) is a common preventable and treatable disease, characterized persistent airflow limitation that usually progressive associated with an enhanced chronic inflammatory response in the airways lung to noxious particles or gases. Objectives-To evaluate outcome of NIV terms ofTime reversio...

Introduction: Chronic obstructive pulmonary disease (COPD) secondary to sulfur mustard gas poisoning, known as mustard lung, is a major late pulmonary complications in chemical warfare patients. Serious comorbidities like dyslipidemia are frequently encountered in COPD. The aim of this study was to measure the serum lipid profile and evaluate the relation of lipid parameters with the severity o...

Evidence has been accumulating that chronic inactivity leading to muscle disuse is unlikely to be the only explanation for the peripheral muscle dysfunction of chronic obstructive pulmonary disease (COPD) patients. Although a new concept of myopathy was recently proposed, the question of disuse and/or a form of myopathy is still being debated. This review proposes definitions for the terms used...

Abbreviations: chronic obstructive pulmonary disease, COPD; quality adjusted life years, QALYs; forced expiratory volume in 1 second, FEV1; forced vital capacity, FVC Citation: Pinnock H, Sohanpal R. Editorial-Chronic obstructive pulmonary disease: reduced nihilism, but there is still a ways to go. Chronic Obstr Pulm Dis (Miami). 2016; 3(3): 605-609. doi: http://dx.doi.org/10.15326/jcopdf.3.3.2...

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and not well understood. The forced expiratory volume in one second is used for the diagnosis and staging of COPD, but there is wide acceptance that it is a crude measure and insensitive to change over shorter periods of time. Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) is a 3-yr ...

Chronic obstructive pulmonary disease (COPD) is prevalent (13.4% in the population above age of 40) but less recognized by patients and physicians Korea. The definition treatment strategies COPD have changed with accumulation evidence, Korean guidelines recommended Academy Tuberculosis Respiratory Disease also been updated. This review will cover some important points, that should be considered...

The purpose of this paper was to systematically search the literature on (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) in the management of chronic obstructive pulmonary disease (COPD) and to provide a concise review of the reported results. Papers were searched through PubMed, EMBASE and Cochrane Library using the MESH terms "pulmonary disease, chronic obstructive", "pu...

Interleukin (IL)-18 production and pulmonary function were evaluated in patients with chronic obstructive pulmonary disease (COPD) in order to determine the role of IL-18 in COPD. Immunohistochemical techniques were used to examine IL-18 production in the lungs of patients with very severe COPD (Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage IV, n = 16), smokers (n = 27) an...