نتایج جستجو برای: cigarette smoking extracts cse

تعداد نتایج: 195621  

Journal: :medical journal of islamic republic of iran 0
yasser labbafinejad occupational medicine department and occupational medicine research center of iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)سازمان های دیگر: occupational medicine research center saber mohammadi occupational medicine department and occupational medicine research center of iran university of medicasciences, tehran, iran.lسازمان های دیگر: occupational medicine research center mirsaeed attarchi occupational medicine department and occupational medicine research center of iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)سازمان های دیگر: occupational medicine research center mashallah aghilinejad occupational medicine department and occupational medicine research center of iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)سازمان های دیگر: occupational medicine research center

abstract   background : noise is the most common hazard in the workplace and noise induced hearing loss considered to be the most common occupational disease as well. cigarette smoking, in some studies, has been known to induce hearing loss. the purpose of this study was to evaluate the effect of contemporary exposure to occupational noise and cigarette smoking on hearing.   methods : 478 assem...

2013
Saskia A. Overbeek Saskia Braber Pim J. Koelink Paul A. J. Henricks Esmaeil Mortaz Adele T. LoTam Loi Patricia L. Jackson Johan Garssen Gerry T. M. Wagenaar Wim Timens Leo Koenderman J. Edwin Blalock Aletta D. Kraneveld Gert Folkerts

BACKGROUND Cigarette smoking induces inflammatory responses in all smokers and is the major risk factor for lung disease such as chronic obstructive pulmonary disease (COPD). In this progressive disease, chronic inflammation in the lung contributes to lung tissue destruction leading to the formation of chemotactic collagen fragments such as N-acetylated Proline-Glycine-Proline (N-ac-PGP). The g...

2012
Graziano Colombo Ranieri Rossi Nicoletta Gagliano Nicola Portinaro Marco Clerici Andrea Annibal Daniela Giustarini Roberto Colombo Aldo Milzani Isabella Dalle-Donne

Different studies reported the presence of oxidized (carbonylated) albumin in the extravascular pool, but not in the intravascular one of cigarette smokers. In this study we attempted to explain this apparent discrepancy exposing human serum albumin (HSA) to aqueous cigarette smoke extract (CSE). CSE induces HSA carbonylation and oxidation of the HSA Cys34 sulfhydryl group. An antioxidant actio...

Journal: :American journal of physiology. Cell physiology 2009
Kurt M Bertram Carolyn J Baglole Richard P Phipps Richard T Libby

Cigarette smoke is the most important environmental risk factor for developing age-related macular degeneration (AMD). Damage to the retinal pigment epithelium (RPE) caused by cigarette smoke may underlie the etiology of AMD. This study investigated the molecular and cellular effects of cigarette smoke exposure on human RPE cells. ARPE-19 or primary human RPE cells were exposed to cigarette smo...

Journal: :Thorax 2013
Cristina Rius Chantal Company Laura Piqueras Jose Miguel Cerdá-Nicolás Cruz González Emilio Servera Andreas Ludwig Esteban J Morcillo Maria-Jesus Sanz

BACKGROUND Cigarette smoking is an important risk factor for the development of cardiovascular disease, yet the pathways through which this may operate are poorly understood. Therefore, the mechanism underlying cigarette smoke (CS)-induced arterial endothelial dysfunction and the potential link with fractalkine/CX(3)CL1 upregulation were investigated. METHODS AND RESULTS Stimulation of human ...

2016
Ailing Liu Jinxiang Wu Aijun Li Wenxiang Bi Tian Liu Liuzhao Cao Yahui Liu Liang Dong

OBJECTIVES Cellular senescence is a state of irreversible growth arrest induced either by telomere shortening (replicative senescence) or stress. The bronchial epithelial cell is often injured by inhaled toxic substances, such as cigarette smoke. In the present study, we investigated whether exposure to cigarette smoke extract (CSE) induces senescence of bronchial epithelial cells; and Cordycep...

2017
Dongmei Huang Zhiying Ma Yili He Ying Xiao Honglin Luo Qiuli Liang Xiaoning Zhong Jing Bai Zhiyi He

Long-term cigarette smoke induces lung inflammatory injury and chronic obstructive pulmonary disease (COPD), associated with skeletal muscle inflammation. This study aimed at investigating how cigarette smoke promotes skeletal muscle inflammation and its molecular pathogenesis. Mice were exposed to air or cigarette smoke for 12 or 24 weeks, and C2C12 cells were stimulated with cigarette smoke e...

2011
Juhi Bagaitkar Carlo A. Daep Carol K. Patel Diane E. Renaud Donald R. Demuth David A. Scott

Smoking is responsible for the majority of periodontitis cases in the US and smokers are more susceptible than non-smokers to infection by the periodontal pathogen Porphyromonas gingivalis. P. gingivalis colonization of the oral cavity is dependent upon its interaction with other plaque bacteria, including Streptococcus gordonii. Microarray analysis suggested that exposure of P. gingivalis to c...

2017
Feng Xu Xiao-Chun Liu Li Li Chao-Nan Ma Ya-Jun Zhang

BACKGROUND We investigated the effects of TRPC1 on epithelial mesenchymal transition (EMT) in human airway in chronic obstructive pulmonary disease (COPD). METHODS A total of 94 patients who underwent lobectomy were selected and divided into COPD (49 cases) and control (45 cases) groups. Immunohistochemistry was applied to detect expression of E-cadherin and vimentin and TRPC1. Correlation of...

Journal: :international journal of high risk behaviors and addiction 0
hossein ali khazaei department of immunology and hematology, research center for clinical immunology, ali ebne abi taleb hospital, zahedan university of medical sciences, zahedan, ir iran bahman khazaei ali ebne abi taleb hospital, zahedan university of medical sciences, chabahar branch, zahedan, ir iran; ali ebne abi taleb hospital, zahedan university of medical sciences, chabahar branch, zahedan, ir iran. tel: +98-5433224122, fax: +98-5433295563 gholam ali dashtizadeh department of ent, faculty of medicine, ali ebne abi taleb hospital, zahedan university of medical sciences, zahedan, ir iran mahdi mohammadi department of biostatistics and health promotion research center, zahedan university of medical sciences, zahedan, ir iran

conclusions our findings did not support the effect of cigarette smoking on spt reactivity to pollen and weeds aeroallergens. however, male were significantly more sensitive than female in terms of sensitivity to some allergens. results the results of this study indicated that 41.4% of patients with allergic rhinitis was smoker with ages ranged from 15 to 70 years. the result of this study also...

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