A71-year-old man with a medical history of hypertension and chronic renal failure presented to the emergency room with chest discomfort and dyspnea for 12 hours. The findings of the ECG (Figure 1) showed acute inferolateral ST-segment elevation myocardial infarction. The first troponin-I, creatine phosphokinase, and creatine kinase (CKMB) measurements were 19.3 ng/mL, 575U/L, and 68.6 ng/mL, re...

We describe the case of an elderly woman whose symptoms and electrocardiographic pattern initially suggested acute myocardial infarction. The value for total serum creatine kinase (EC 2.7.3.2; CK) was 737 U/L (reference interval: 22269 U/L), and electrophoresisfor CK isoenzymes demonstrated two bands, the more anodal migrating to the CK-MB region and the second migrating between the CK-MB and C...

Persistent atrial fibrillation is one of the most common arrhythmias, which is caused by disorderly excited and invalid contract room sex rhythm in patients with arrhythmia. Evidences have indicated that plasma concentration levels of bilirubin and serum uric acid are associated with progression of auricular fibrillation. In this clinical investigation, regression analysis between auricular fib...

Results Mean baseline BNP was significantly higher in VR (304.01 vs 105.8 pg/ml, p < 0.001), although baseline LVEF (54.4% vs 52.5%) was similar in both. Pre-operative Tn-I and CK-MB levels were higher in those undergoing OPCABG. Biomarker release kinetics were significantly different amongst two groups. All three biomarkers increased rapidly within 6 hours of OPCABG. In VR group, BNP levels in...

Objectives Coronavirus 2019 disease (COVID-19) lead to one of the pandemics last century. We aimed predict poor prognosis among severe patients early intervention. Methods The data 534 hospitalized were assessed retrospectively. Risk factors and laboratory tests that might enable prediction defined as being transferred intensive care unit and/or exitus have been investigated. Results At admissi...

BACKGROUND/AIMS Patients requiring haemodialysis have cardiovascular and immune dysfunction. Little is known about the acute effects of exercise during haemodialysis. Exercise has numerous health benefits but in other populations has a profound impact upon blood pressure, inflammation and immune function; therefore having the potential to exacerbate cardiovascular and immune dysfunction in this...

Background and Aims. Neutrophil extracellular traps (NETs) have been identified in acute myocardial infarction. We assessed the time profile and association with infarct size for NETs markers in ST-elevation myocardial infarction (STEMI) and stable angina pectoris (AP). Methods. In 20 patients with STEMI and 10 with AP undergoing percutaneous coronary intervention (PCI), blood samples were coll...

Results of an immunoenzymetric assay (TANDEM-E CKMB) for creatine kinase (CK; EC 2.7.3.2) MB isoenzyme, in which subunit-specific monoclonal antibodies are used, were compared with those by an immunochemical method (Isomune-CK) and electrophoresis (Corning agarose gel). The study involved 200 patients; greater than 500 samples were analyzed by all three methods. The analytical performances were...

Results of the "Tandem-E CKMB" immunoenzymometric procedure (y) for creatine kinase (CK; EC 2.9.3.2) were compared with electrophoresis (x) for 160 serum samples from patients suspected of having sustained myocardial infarctions. The results correlated well: y, microgram/L (Tandem assay) = 1.3x-6.3 U/L(electrophoresis) (r = 0.95). CK-MB mass measurement was more stable than enzyme activity afte...

Objective: To detect doxorubicin-induced myocardial injury by quantitative estimation of cardiospecific protein, Cardiac Troponin I (cTnI) at early stage and to evaluate the cardioprotective effects of α-Tocopherol. Study Design: Lab based randomized controlled in-vivo study in rabbits. Place and Duration of Study: Department of Pharmacology in collaboration with Pathology department, Army Medi...