BACKGROUND To compare the metabolic effects on lipids and acceptability and safety of, and compliance with, a continuous administration of conjugated estrogen plus medroxyprogesterone acetate (Premelle) versus a placebo in non-hysterectomized postmenopausal women. METHODS Sixty-six generally healthy, female, early post-menopausal women, from 45-60 years of age, were randomized for an administ...

To assess the safety and efficacy of oestriol in relieving post-menopausal symptoms 53 post-menopausal Japanese women with climacteric symptoms, 27 with natural menopause (group I) and 26 with surgically induced menopause (group II), received oral oestriol, 2 mg daily for 12 months. Clinical parameters including Kupperman index (KI) and the degree of satisfaction with symptomatic relief; serum ...

In the historical period it was commonly held that estrogen had two principal benefits to postmenopausal women: 1) To alleviate the constitutional symptoms related to the climacteric such as vasomotor symptoms (hot flushes), night sweats, somnolence, and vaginal dryness; and, 2.) To work in concert with weight-bearing exercise and diet replete with calcium to decrease or minimize their role in ...

BACKGROUND Climacteric symptoms such as hot flushes and vaginal dryness are very common in breast cancer patients, resulting either from age or adjuvant therapy. Tibolone, a synthetic steroid, is effective in reducing these symptoms in healthy post-menopausal women, but this has never been studied in a large breast cancer population. OBJECTIVES The primary objective of LIBERATE trial was to s...

background : postmenopausal hot flash is a common disease amongst women with high prevalence of 75%. hormone replacement therapy (hrt) is a well-known relief of symptoms which has disadvantages such as side effects and contraindication for certain types of hormone related diseases and breast or estrogen related cancers. one of the alternatives is acupuncture which is an east asian and more spec...

Ripening of ;Tydeman's Early' apples (Malus sylvestris L.) assessed by the occurrence of the respiratory climacteric was delayed by succinic acid 2,2-dimethyl hydrazide (B-9) but not by 2-chloroethyltrimethylammonium chloride (CCC), each applied 14 days after bloom. B-9 also inhibited ethylene production by fruits exhibiting the climacteric rise. Inhibition of the climacteric by B-9 was overcom...

The aim of this work was to evaluate the effect of 1-methylcyclopropene (1-MCP) treatment on the development of chilling injury (CI) symptoms in four plum cultivars and to determine the relationship between the climacteric behavior of the cultivar and its sensitivity to this disorder. Significant differences in ripening pattern were found between the cultivars after long-term storage. Among the...

OBJECTIVE To examine prospectively the relationship between prenatal life stress and infant crying/fussing during the first 6 months of postnatal life, taking into account an array of confounders suggested in the literature. DESIGN Prospective longitudinal study of a convenient sample, with data points in pregnancy and at about 6 weeks, 3, and 6 months postpartum. METHODS The study included...

This study used a multiple regression model of change in a longitudinal framework to examine the relationship between changes in social support and psychological maladjustment, controlling for initial maladjustment and initial levels of life change and social support. Respondents were a randomly selected community sample of 245 male and 248 female adult family members who completed two surveys ...