Autism is a severe and the most heritable developmental disorder, whose pathogenesis is still largely unknown. The rising incidence of autism in the last decade has increased the scientific interest and research. More than a thousand papers concerned with information about the etiology of this "static disorder of the immature brain" can be found on Pub Med. The aim of this paper is to give a re...

I HAVE BEEN interested in the malabsorption syndromes for a long time and one of the fascinations of a continued interest over the years is to watch the emphasis change as new knowledge is added and old problems are solved. When I reviewed the subject in 1960 the classical idea that all the signs and symptoms of the malabsorption syndromes were due to failure of absorption of essential substanc...

Periodic fever syndromes (PFSs) are a wide group of autoinflammatory diseases. Due to some clinical overlap between different PFSs, differential diagnosis can be a difficult challenge. Nowadays, there are no universally agreed recommendations for most PFSs, and near half of patients may remain without a genetic diagnosis even after performing multiple-gene analyses. Molecular analysis of period...

The aim of this review is to outline the clinical presentation, pathophysiology and evaluation lower urinary tract (LUT) dysfunction in Parkinson’s disease other parkinsonian syndromes including multiple system atrophy, dementia with Lewy bodies, progressive supranuclear palsy corticobasal degeneration. LUT commonly occurs neurological disorders, patients syndromes. pattern its severity are var...

A 12 year old boy presented with the clinical picture of secondary mania. Neuropsychological examination revealed significant prefrontal disturbance. The overlap in the clinical presentation of secondary mania and frontal lobe syndromes is highlighted. At least some of the so called frontal lobe syndromes can he considered as secondary mania.

The present study examined the prevalence and correlates of clinical syndromes in a large group ( N = 438) of incarcerated violent offenders, looking at differences between inmates with one and those with more than one clinical syndromes. More than a half of the sample (57%) reported clinically relevant symptoms for at least one clinical syndrome ( n = 252), and the majority of them (38%) repor...

Article abstract-Objectiue: To improve clinical recognition and provide research diagnostic criteria for three clinical syndromes associated with frontotemporal lobar degeneration. Methods: Consensus criteria for the three prototypic syndromes-frontotemporal dementia, progressive nonfluent aphasia, and semantic dementia-were developed by members of an international workshop on frontotemporal lo...

Background. To simplify traditional Chinese medicine syndrome differentiation and allow researchers to master syndrome differentiation for hypertension, this paper retrospectively studied the literature and analyzed syndrome elements corresponding to hypertension syndromes. Methods. Six databases including PubMed, EMBASE, Chinese Bio-Medical Literature Database, Chinese National Knowledge Infra...