Oral lichen planus (OLP) is a common oral inflammatory condition. Against symptomatic atrophic-erosive OLP, topical steroids, or photobiomodulation (PBM) are deployed. Optical coherence tomography (OCT) provides real-time, non-invasive, tissue investigation. Aim of this study was to evaluate modifications OCT pattern in patients with painful before and after treatment PBM, comparing those resul...

The morpholinium cation based ionic liquids are designed to evaluate the thermophysical, chemical reactivity, and biological activity. To estimate and design the bioactive ILs, propionate and trihalopropanoate were considered under theoretical study by Density Functional Theory (DFT). To make effect of halogens atom on anion, propionate, trifluro propionate, trichloro propionate, and tribromo p...

Objectives: To study the epidemiological distribution of disease lichen planus and its therapeutic management. Methods: A total 174 patients with a diagnosis between 2008 2017 at Portuguese public hospital were included in this retrospective study. The following data collected from clinical records: gender, age, topographic lesions, prescribed therapy (active substance, route, scheme administra...

The enzymatic potential of the cultured plant cells can be employed for bioconversion purposes. Plant enzymes are able to catalyze regio- and stereo-specific reactions, and therefore can be applied for the production of desired substances. The biotransformation of foreign substrates with suspension cells of Peganum harmala was tested with (±) phenylethyl propionate. The callus cultures of Pegan...

The morpholinium cation based ionic liquids are designed to evaluate the thermophysical, chemical reactivity, and biological activity. To estimate and design the bioactive ILs, propionate and trihalopropanoate were considered under theoretical study by Density Functional Theory (DFT). To make effect of halogens atom on anion, propionate, trifluro propionate, trichloro propionate, and tribromo p...

Abstract Intravenous immunoglobulins (IVIg) have been used in clinical practice for more than 50 years. They are dermatological indications such as dermatomyositis, pemphigus and Kawasaki disease. Although this is regarded a safe treatment modality, it can produce adverse reactions the skin. We report two patients with IVIg-induced skin changes. A 71-year-old man no preceding disease was under ...

Acute generalized exanthematous pustulosis (AGEP) is a dramatic generalized pustular rash of severe onset, which is considered a serious cutaneous adverse reaction to drugs. However, even though the clinical features are impressive and are often accompanied by systemic inflammation, it can be controlled quickly and safely by topical steroids subsequent to interruption of the offending drug. Her...

A 55-year-old male developed itching on the anterior aspects of both legs and the right ankle. Gradually over the next 5 years there was thickening of the skin on these areas followed by the appearance of hyperpigmented, scaly, severely itchy plaques. He also noticed the appearance of a thick, hard horn-like structure projecting from the surface of the right ankle lesion for the last 2 years. A...