The DIL-frequency study aims to establish the optimal dose and repeat dosing schedule (interval) to administer ultra-low dose Interlekin-2 to participants with type 1 diabetes in order to target a desired regulatory T cell (Treg) increase and increased CD25 expression on Tregs and a minimal increase of CD4 T effector cells (Teffs). Before the start of the trial, the available doses are chosen w...

This study presents a large-scale monitoring of marine litter performed in the joint Norwegian–Russian ecosystem monitoring surveys in the period from 2010 to 2016 and contribute to documentation of the extent of marine litter in the Barents Sea. The distribution and abundance of marine litter were calculated by recordings of bycatch from the pelagic trawling in upper 60m, from bottom trawling ...

We introduce a data processing pipeline designed to generate registration markers from range scan data. This approach uses curvature maps and histogram-templates to identify local surface features. The noise associated with real-world scans is addressed using a (common) Gauss filter and expansion-segmentation. Experimental results are presented for data from The Digital Michelangelo Project.

In this presentation, we describe an implicit Closest Point Method [3] which allows large, stable time steps for high-order PDEs while retaining the principal benefits of the original method. Example computations (including the in-surface heat equation, reaction-diffusion on surfaces, Laplace–Beltrami eigenmodes, and fourth-order interface motion) on a variety of surfaces demonstrate the effect...

BAN estimators generally admit first order representations which insure them to be also asymptotically Pitman closest. For AN estimators admitting a first order representation, an ordering under the Pitman closeness measure is established and is shown to be isomorphic to the one under 'the usual quadratic norm. Multiparameter problems are also treated in the same vein.

Article history: Received 24 April 2009 Received in revised form 15 January 2010 Available online 25 January 2010 Communicated by Y. Liu