AIMS Cenderitide is a novel dual natriuretic peptide (NP) receptor chimeric peptide activator, which targets the particulate guanylyl cyclase B (pGC-B) receptor and pGC-A unlike native NPs. Cenderitide was engineered to retain the anti-fibrotic properties of C-type natriuretic peptide (CNP)/pGC-B with renal-enhancing actions facilitated by fusion to the carboxyl terminus of Dendroaspis NP (DNP)...

We demonstrate analytically the technique and arrangement of nanoparticle antenna arrays with enhancement optical characteristics at an frequency regime. The array are enhanced by introducing inverse active spherical coated (I-CNP). This is designed combined already demonstrated CNPs. Consequently, three types CNPs their inverse-based plasmonic nano-antenna configurations have been studied: two...

We report on transport properties in dual-gated hexagonal boron nitride (hBN)/bilayer-graphene (BLG) superlattices. Here, BLG is nontwisted, i.e., plain. This paper focuses the charge neutrality point (CNP) for a plain BLG. Under perpendicular magnetic field, transitions between two insulating phases at CNP are detected by varying displacement field with study resistance-temperature characteris...

The multifaceted process of immune cell recruitment to sites of tissue injury is key to the development of an inflammatory response and involved in the pathogenesis of numerous cardiovascular disorders. We recently identified C-type natriuretic peptide (CNP) as an important endothelium-derived mediator that regulates vascular tone and protects against myocardial ischemia/reperfusion injury. Her...

Production and clearance of plasma C-type natriuretic peptide (CNP) and amino terminal (NT)-proCNP immunoreactivity in the human circulation remain poorly characterized. Accordingly, we have measured arterial and venous concentrations of CNP and NT-proCNP across multiple tissue beds during cardiac catheterization in 120 subjects (age: 64.2+/-9.0 years; 73% men) investigated for cardiovascular d...

In this work, the capacity of wastewater from an inland fishery system in Colombia (Norte de Santander) was tested as culture medium for Chlorella sp. and Scenedesmus Due to insufficient N P concentrations successful algae growth, effect replenishment with NO3, PO4, Na2CO3 or NaHCO3 a carbon source analyzed using three-factor nonfactorial response surface design. The results showed that additio...

PURPOSE. To evaluate the potential neuroprotective effects of C-type natriuretic peptide (CNP) on rat retinal ganglion cells (RGCs). METHODS. Cultured adult rat retinal cells were treated with vehicle, CNP, or atrial natriuretic peptide (ANP), followed by cytotoxic insults (glutamate, TNFalpha, or withdrawal of trophic factor). RGC survival was analyzed by counting Thy-1-positive cells in each ...

The Federal Reserve Banks of Boston and Atlanta convened a meeting of the Mobile Payments Industry Workgroup (MPIW) in November 2015 to discuss payments in the card-not-present (CNP) environment. Not only are consumers increasingly using mobile devices to initiate CNP payments; but the e-commerce fraud rate in the U.S. is expected to increase significantly as EMV2 chip card migration progresses...

In adult rat testes, the blood-testis barrier (BTB) in the seminiferous epithelium must "open" (or "disassemble") to accommodate the migration of preleptotene spermatocytes from the basal to the adluminal compartment that occurs at stage VIII of the epithelial cycle. However, the molecule(s) and/or mechanism(s) that regulate this event are unknown. In this report, C-type natriuretic peptide (CN...