5-HT2 receptor activity in the hypoglossal nucleus and hypercapnia is associated with airway dilation. 5-HT neurons in the medullary raphe and hypercapnia are responsible for tidal volume change. In this study, the effects of 5-HT2 receptors in the dorsomedial medulla oblongata (DMM), which receives projections from the medullary raphe, and hypercapnia on airway resistance and respiratory varia...

BACKGROUND Volume-outcome relationships related to major surgery may be of limited value if observation ends at the point of discharge without taking transfers and later events into consideration. METHODS The volume-outcome relationship in patients who underwent pancreatic surgery between 2008 and 2010 was assessed using claims data for all inpatient episodes from Germany's largest provider o...

This paper is concerned with the construction of a fast algorithm for computing the maximum speed of propagation in the Riemann solution for the Euler system of gas dynamics with the co-volume equation of state. The novelty in the algorithm is that it stops when a guaranteed upper bound for the maximum speed is reached with a prescribed accuracy. The convergence rate of the algorithm is cubic a...