Fibrinogen is essential for the formation of a fibrin clot. Acquired and congenital disorders of fibrinogen may result in decreased concentration or altered function of fibrinogen, often leading to an increased risk of bleeding. Routine coagulation testing and specialized laboratory investigations can guide diagnosis in patients suspected of having a fibrinogen abnormality. This article summari...

Congenital platelet pathology refers to disorders of platelet function, the red cells being essential for the coagulation of blood. Congenital platelet disorders are important causes of bleeding that can quantitatively and qualitatively alter platelets, impairing their function. The purpose of this study is to summarize current knowledge on the different types of inherited platelet disorders, t...

The article presents a literature review on the study of relationship FGA, FGB, F2, F5, PAI, ITGA2 gene polymorphisms with development pulmonary embolism (PE). We concluded that genetic factors in PE are to greater extent mutations genes. There is positive correlation between presence combined and PE. allelic polymorphism hemostasis genes makes it possible predict coagulation system disorders, ...

Background: Hemiscorpius lepturus envenomation is one of the most important medical issues in tropical regions of Iran, especially Khuzestan Province. Due to lack of reliable data about scorpion sting in Khuzestan Province, this investigation was performed to study the clinical presentation, prognosis factors, complications and mortality rates of Hemiscorpius lepturus sting. Methods: this study...

Background: Bleeding assessment tools are key components in the evaluation of patients suspicious for bleeding disorders. The exact determination of the normal ranges of ISTH-BAT (International Society on Thrombosis and Hemostasis –Bleeding Assessment Tool) in the healthy population is a crucial step for determining who needs to be referred for further coagulation laboratory examinations. We ai...