Triple therapy for COPD consists of a long-acting anti-cholinergic bronchodilator, a long-acting beta-agonist bronchodilator, and an inhaled corticosteroid. Guidelines from the Canadian Thoracic Society advocate triple therapy for some patients with moderate-to-severe COPD. The objective of this review was to evaluate the evidence based clinical efficacy of triple therapy compared to dual bronc...

The doubleand triple-photoionization process in which two (or three) electrons are simultaneously emitted from an atom is of fundamental importance for the understanding of electron correlation. The triple-to-single photoionization ratio is a convenient way to quantify this correlation and to investigate its photon energy dependence. Many experimental and theoretical investigations have dealt w...

PURPOSE Although tiotropium (TIO) and inhaled corticosteroid (ICS)/long-acting β-agonists are frequently prescribed together, the efficacy of "triple therapy" has not been scientifically demonstrated. We conducted a systematic review and meta-analysis using Bayesian methods to compare triple therapy and TIO monotherapy. METHODS We searched the MEDLINE, EMBASE, and Cochrane Library databases f...

Semantic inferencing and querying across largescale RDF triple stores is notoriously slow. Our objective is to expedite this process by employing Google’s MapReduce framework to implement scale-out distributed querying and reasoning. This approach requires RDF graphs to be decomposed into smaller units that are distributed across computational nodes. RDF Molecules appear to offer an ideal appro...

Characterization of the drift in the 18-GHz brightness temperature (TB) measured by the TOPEX microwave radiometer (TMR) is presented. The appropriate correction is not a constant drift but varies with TB. Using this correction results in a more accurate path delay retrieval that varies appropriately with cloud cover and surface wind speed.