BACKGROUND Tinnitus and headache are frequent disorders. Here, we aimed to investigate whether the occurrence of headache among tinnitus patients is purely coincidental or whether tinnitus and headache are pathophysiologically linked. We investigated a large sample of patients with tinnitus and headache to estimate prevalence rates of different headache forms, to determine the relationship betw...

Although controversial, diminished activity of 5,10 methylenetetrahydrofolate reductase (MTHFR), a regulatory enzyme of homocysteine metabolism, may predispose to migraine in Turkish people. In a case-control study, we determined the prevalence of two common MTHFR polymorphisms,C677T and A1298C, in 102 migraine patients (23 migraine with aura, 70 migraine without aura and nine with tension-type...

INTRODUCTION MIDAS is a valid and reliable short questionnaire for assessment of headache related disability. Linguistic validation of Persian MIDAS and assessment of psychometric properties between tension type headache (TTH) and migraine were the aims of this study. METHODS Patients with migraine or TTH were included. At the first visit, we administered a headache symptom questionnaire, MID...

Ophthalmoplegic migraine is a rare disorder characterized by childhood onset recurrent attacks of migraineous headaches with paresis of ocular cranial nerves. The third cranial nerve is commonly involved. Involvement of fourth and sixth cranial nerve is uncommon. We present a child with opthalmoplegic migraine with recurrent sixth cranial nerve palsy on two occasions. Neurology Asia 2013; 18(1)...

Objective To review the role of CGRP in human models of primary headaches and to discuss methodological aspects and future directions. Discussion Provocation experiments demonstrated a heterogeneous CGRP migraine response in migraine patients. Conflicting CGRP plasma results in the provocation experiments are likely due to assay variation; therefore, proper validation and standardization of an ...

Abstract Background Headache is the most common pain disorder , affecting around 66% of global population. This study aimed to investigate efficacy high-frequency repetitive transcranial magnetic stimulation (rTMS) in treating patients with primary chronic daily headaches (chronic tension-type headache and migraine). Methods Twenty-seven participated study, divided into 2 groups: a group (16 pa...

Several family practitioners have told me that their hearts sink when a patient comes into the surgery complaining of migraine. I can sympathise with this feeling if the waiting room is full; it takes several minutes to establish a diagnosis, and a few more to find out the particular patient's triggering factors and then to explain and prescribe the appropriate treatment. The patient may theref...

Background: Migraine and tension-type headache are primary headache disorders that occur during pregnancy. Most women with migraine improve during pregnancy. Some women have their first attack during pregnancy. Migraine can recur postpartum; it can also begin at that time. Women who have had menstrual migraine and migraine onset at menarche tend to experience no migraine during pregnancy. Not a...