Inhibition of angiogenesis is considered as one of the desirable pathways for the treatment of tumor growth and metastasis. Herein we demonstrated that a series of pyridinyl-thiazolyl carboxamide derivatives were designed, synthesized and examined against angiogenesis through a colony formation and migration assays of human umbilical vein endothelial cells (HUVECs) in vitro. A structure-activit...

In this paper, the cooperative diversity is investigated in the uplink of a Code Division Multiple Access (CDMA) network in which users cooperate by relaying each other’s messages toward the Base Station (BS). It is assumed that the spreading waveforms are not orthogonal and hence, Multiple Access Interference (MAI) exists at the relay nodes as well as the BS. MAI degrades the signal quality at...

Mobile Ad hoc Networks are characterized by multi-hop wireless links, without any infrastructure and frequent node mobility. A class of ant colony based routing protocols has recently gained attention because of their adaptability to the network changes. AntHocNet is ant colony based hybrid algorithm, which combines reactive path setup with proactive path probing, maintenance and improvement. M...

Lysobacter enzymogenes strain C3 is a gliding bacterium which produces the antifungal secondary metabolite heat-stable antifungal factor (HSAF) and type IV pilus (T4P) as important mechanisms in biological control activity against fungal pathogens. To date, the regulators that control HSAF biosynthesis and T4P-dependent twitching motility in L. enzymogenes are poorly explored. In the present st...

Flavobacterium psychrophilum is an important fish pathogen, responsible for Cold Water Disease, with a significant economic impact on salmonid farms worldwide. In spite of this, little is known about the bacterial physiology and pathogenesis mechanisms, maybe because it is difficult to manipulate, being considered a fastidious microorganism. Mutants obtained using a Tn4351 transposon were scree...

An efficient retrieval of a relatively small number of relevant cases from a huge case base is a crucial subtask of Case-Based Reasoning (CBR). In this article, we investigate Case Retrieval Nets, a memory model for this task which is applicable in any domain with attribute-based case representations. The main idea is to apply a restricted spreading activation process in the case memory in orde...

The present study was an attempt to replicate and extend Brown's (1979) finding of inhibition in retrieval from semantic memory produced by presentation of semantically related primes. Subjects' speed and accuracy in answering generalknowledge questions (e.g., Who was the first man to walk on the moon?) were measured when the question was preceded by one of four different prime types: neutral (...

We study the diffusive logistic equation with a free boundary in higher space dimensions and heterogeneous environment. Such a model may be used to describe the spreading of a new or invasive species, with the free boundary representing the expanding front. For simplicity, we assume that the environment and the solution are radially symmetric. In the special case of one space dimension and homo...

Models of automatic priming of word identification can be divided into those based on associative relations (e.g., spreading activation) and others based on semantic similarity (e.g., distributed models). In three experiments, associative relatedness was manipulated by presenting asymmetrically associated word pairs in both their forward and backward directions. Priming was comparable in both d...

evaluation of changes present in soil and water resources due to operation implement of floodwater spreading is necessary to assess their positive or negative resultant effect. rate of the internal sediment to diversion spreader channels, surface sedimentation and aggregation of the spreading field depth are most important effective attributes on the yield of floodwater spreading systems. these...