unfortunately, many people, including many psychotherapists, mistakenly think that obsessive-compulsive disorder (ocd) in children and adolescents is rare. recent research indicates that approximately half of all adults with ocd experience clinical symptoms of the disorder during their childhood. ocd in childhood is a chronic and distressing disorder that can lead to severe impairments in socia...

Nuclear magnetic resonance (NMR) spectroscopy is the prime technique for studying molecular and biomolecular structure as well as dynamics. The time domain NMR signal can be ideally modelled as the sum of damped complex exponentials in additive Gaussian noise. The spectrum of the signal may contain regions having overlapping peaks. In order to understand the underlying chemical structure, these...

A Bernoulli random walk is a random trajectory starting from 0 and having i.i.d. increments, each of them being +1 or −1, equally likely. The other families cited in the title are Bernoulli random walks under various conditionings. A peak in a trajectory is a local maximum. In this paper, we condition the families of trajectories to have a given number of peaks. We show that, asymptotically, th...

Summary: Chromaligner is a tool for chromatogram alignment to align retention time for chromatographic methods coupled to spectrophotometers such as high performance liquid chromatography and capillary electrophoresis for metabolomics works. Chromaligner resolves peak shifts by a constrained chromatogram alignment. For a collection of chromatograms and a set of defined peaks, Chromaligner align...

MOTIVATION Comparative metabolic profiling by nuclear magnetic resonance (NMR) is showing increasing promise for identifying inter-individual differences to drug response. Two dimensional (2D) (1)H (13)C NMR can reduce spectral overlap, a common problem of 1D (1)H NMR. However, the peak alignment tools for 1D NMR spectra are not well suited for 2D NMR. An automated and statistically robust meth...