نتایج جستجو برای: comparative genomics
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The field of comparative genomics arose hand-in-hand with the ability to generate genomic sequence data. The first computer algorithms to compare amino acid sequences were developed over forty years ago (Fitch 1966; Needleman and Wunsch 1970)and improved upon as nucleic acid sequencing advanced (Sanger et al. 1977) with the application of improved statistical methods to the growing database of ...
Traditional biology has changed dramatically in the past two decades to the degree that advancements in the 21st century will be dominated by research at the convergence of biological, physical, and information sciences. Driven by large scientific endeavors such as the human genome project, it has become very much an information science, closely tied to tools and methods of the mathematical sci...
The family Brassicaceae is one of the major groups of the plant kingdom and comprises diverse species of great economic, agronomic and scientific importance, including the model plant Arabidopsis. The sequencing of the Arabidopsis genome has revolutionized our knowledge in the field of plant biology and provides a foundation in genomics and comparative biology. Genomic resources have been utili...
Genome Browsers are software that allow the user to view genome annotations in the context of a reference sequence, such as a chromosome, contig, scaffold, etc. The Generic Genome Browser (GBrowse) is an open-source genome browser package developed as part of the Generic Model Database Project (see UNIT ; Stein et al., 2002). The increasing number of sequenced genomes has led to a corresponding...
Cryptochromes are flavoproteins that play a central role in the circadian oscillations of all living organisms except archaea. Cryptochromes are clustered into three subfamilies: plant-type cryptochromes, animal-type cryptochromes and cryptochrome-DASH proteins. These subfamilies are composed of photolyase/cryptochrome superfamily with 6-4 photolyase and cyclobutane pyrimidine dimer photolyase....
The availability and complete sequencing of many organisms has made comparative analysis of gene a new field of research. The explosion in sequenced genome data on daily basis made this task an enormous one. Several techniques and methods have been devised and applied to carry out genome comparison. In this work, we surveyed and presented an overview of common methods, techniques, tools and cha...
ABC Fax + 41 61 306 12 34 E-mail [email protected] www.karger.com © 2005 S. Karger AG, Basel 0301–0171/05/1083–0006$22.00/0 Accessible online at: www.karger.com/cgr Abstract. Studies of complete genomes are leading to a new understanding of the biology of mammals and providing ongoing insights into the fundamental aspects of the organization and evolution of biological systems. Comparison of pri...
Biologists face an overwhelming richness of nucleotide and protein sequence data. By the middle of 2005, there were almost 300 complete genomes that were publicly accessible. Most of these were archeal or bacterial since prokaryotic genomes are much smaller than eukaryotic genomes. Among eukaryotes, fungi, particularly yeasts, have some of the smallest genome sizes and hence represent the highe...
Our knowledge of yeast genomes remains largely dominated by the extensive studies on Saccharomyces cerevisiae and the consequences of its ancestral duplication, leaving the evolution of the entire class of hemiascomycetes only partly explored. We concentrate here on five species of Saccharomycetaceae, a large subdivision of hemiascomycetes, that we call "protoploid" because they diverged from t...
Three alloherpesviruses are known to cause disease in cyprinid fish: cyprinid herpesviruses 1 and 3 (CyHV1 and CyHV3) in common carp and koi and cyprinid herpesvirus 2 (CyHV2) in goldfish. We have determined the genome sequences of CyHV1 and CyHV2 and compared them with the published CyHV3 sequence. The CyHV1 and CyHV2 genomes are 291,144 and 290,304 bp, respectively, in size, and thus the CyHV...
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