Sole reliance on one drug, Praziquantel, for treatment and control of schistosomiasis raises concerns about development of widespread resistance, prompting renewed interest in the discovery of new anthelmintics. To discover new leads we designed an automated label-free, high content-based, high throughput screen (HTS) to assess drug-induced effects on in vitro cultured larvae (schistosomula) us...

In this paper we consider an extension of the two-dimensional risk model introduced in Avram, Palmowski and Pistorius (2008a). To this end, we assume that there are two insurers. The first insurer is subject to claims arising from two independent compound Poisson processes. The second insurer, which can be viewed as a different line of business of the same insurer or as a reinsurer, covers a pr...

Beagle dogs have long been employed in toxicology studies and as skin disease models. Compared with other experimental animal species, they are known to be susceptible to skin responses, such as rashes, from exposure to various chemical compounds. Here, a unique dog phenotype was identified that showed no skin response to compound 48/80, a mast cell degranulating agent. Although the skin respon...

In this study, organically raised pigs received an increasing proportion of grass silage up to 10 and 20% dry matter in the daily ration in the grower and finisher period, respectively, to determine the effects of grass silage on feed intake and growth performance. The pigs receiving a mixture of grass silage and compound feed ingested 0.3 kg DM/d (13% of their daily ration) as grass silage and...

A new type of waterproofing composite emulsion with high silane content and good economic efficiency was synthesized by sol synthesis. The effects the amount proportion compound emulsifier, tetraethyl orthosilicate, mixing time on properties emulsifier were investigated. optimum conditions for synthesis a orthosilicate/isobutyl triethoxysilane determined. characterized infrared spectroscopy, th...

A proportion of the plant's l-ascorbate (vitamin C) occurs in the apoplast, where it and its metabolites may act as pro-oxidants and anti-oxidants. One ascorbate metabolite is 2,3-diketogulonate (DKG), preparations of which can non-enzymically generate H2O2 and delay peroxidase action on aromatic substrates. As DKG itself generates several by-products, we characterised these and their ability t...

results of total 60 s. aureus isolates, 51 (85%) were mrsa, and of 60 cons, 7 (11.66%) were mrcons. the results showed that the mic of chlorhexidine for all 120 isolates was 1-16 μg/ml. 15 (12.5%) isolates carried qaca/b gene, 26 (21.7%) carried qacc gene, and 38 (31.7%) carried smr gene. conclusions maintenance of mrsa isolates in the attendance of low amounts of antiseptics could result in th...

the acorn is an edible nut of oak trees (quercus spp.) that had been used for human nutrition for a long time. besides nutritious components, acorn contains considerable amounts of phenolic substances. at present study, two different varieties of iranian oak acorns, namely, q. branti var. persica (qb) and qcastaneifolia var. castaneifolia (qc) were used. the total polyphenol content measured in...

a rapid and reproducible method is described that employs solid phase extraction (spe) using dichloromethane, followed by gas chromatograph-mass spectrometry for the determination of toxic toluene, xylene and cumene (txc) from different lake water of dhaka mega city of bangladesh. the method was applied to detect and quantify txc in water samples collected from surface and 30 cm depth of water....

in this paper, the deformation of a thick-walled circular cylindrical shell of incompressible isotropic elastic material is considered. the shell, which is made of three-term strain energy function is subjected to the combined external and axial loading pressure. in order to obtain the relevant eigenvalues, which is the main objective of the work, the incremental equilibrium equations are so...