Actin stress fibers (SFs) of cells cultured on cyclically stretched substrate tend to reorient in the direction in which a normal strain of substrate becomes zero. However, little is known about the mechanism of this reorientation. Here we investigated the effects of cyclic stretch waveform on SF reorientation in osteoblastic cells. Cells adhering to silicone membranes were subjected to cyclic ...

BACKGROUND AND OBJECTIVES Mechanical indentation has been shown to increase light transmission through turbid tissue. In this study, we investigated the effects of localized indentation on the optical properties of ex vivo porcine skin specimens by dynamically monitoring diffuse reflectance spectra, light transmission, and applied load while controlling tissue thickness. STUDY DESIGN/METHODS ...

The compressive response of a three-dimensional (3D) non-interlaced composite comprising three orthogonal sets of carbon fibre tows within an epoxy matrix is analysed. First, the compressive response is measured in three orthogonal directions and the deformation/failure modes analysed by a combination of X-ray tomography and optical microscopy. In contrast to traditional unidirectional and two-...

BACKGROUND Questions regarding the distribution of stress in the proximal human femur have never been adequately resolved. Traditionally, by considering the femur in isolation, it has been believed that the effect of body weight on the projecting neck and head places the superior aspect of the neck in tension. A minority view has proposed that this region is in compression because of muscular f...

Synchrotron X-ray diffraction is used to study in situ the evolution of phase strains during compressive creep deformation in bovine bone and dentin for a range of compressive stresses and irradiation rates, at ambient and body temperatures. In all cases, compressive strains in the collagen phase increase with increasing creep time (and concomitant irradiation), reflecting macroscopic deformati...

Thermal and thermomechanical phenomena in laser metal interaction are of great importance in terms of understanding the underlying mechanisms in laser materials processing, optimizing the efficiency of laser micro-machining, and minimizing laser induced damage. In this work, Molecular Dynamics (MD) simulation is carried out to investigate picosecond laser copper interaction. A method has been d...

This paper presents an investigation of the mechanism of the brittle–ductile cutting mode transition from the perspective of the mechanics. A mechanistic model is proposed to analyze the relationship between undeformed chip thickness, deformation, and stress levels in the elastic stage of the periodic chip formation process, regarding whether brittle or ductile mode deformation is to follow the...

[1] There are currently two competing models for the frictional strength of the San Andreas Fault in California: the strong-fault model and the weak-fault model. The strongfault model predicts the maximum horizontal compressive stress axis to be at low angles to the fault, while the relatively weak fault model predicts it to be at high angles. Previous studies have disagreed as to which model i...

INTRODUCTION This study aimed to explore the effects of TGF-β1 on regulating activities of cementoblasts and osteoblasts with or without stress. MATERIAL AND METHODS Human recombinant TGF-β1 was added with different doses. Immunohistochemical test of osteoprotegerin (OPG)/receptor activator of nuclear factor-kappaB ligand (RANKL) and Alizarin Red-S staining were conducted. Mechanical compress...