نتایج جستجو برای: compulsivity

تعداد نتایج: 298  

Journal: :Neuron 2015
Vincent Pascoli Jean Terrier Agnès Hiver Christian Lüscher

The factors causing the transition from recreational drug consumption to addiction remain largely unknown. It has not been tested whether dopamine (DA) is sufficient to trigger this process. Here we use optogenetic self-stimulation of DA neurons of the ventral tegmental area (VTA) to selectively mimic the defining commonality of addictive drugs. All mice readily acquired self-stimulation. After...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Pin Xu Brad A Grueter Jeremiah K Britt Latisha McDaniel Paula J Huntington Rachel Hodge Stephanie Tran Brittany L Mason Charlotte Lee Linh Vong Bradford B Lowell Robert C Malenka Michael Lutter Andrew A Pieper

Compulsive behavior is a debilitating clinical feature of many forms of neuropsychiatric disease, including Tourette syndrome, obsessive-compulsive spectrum disorders, eating disorders, and autism. Although several studies link striatal dysfunction to compulsivity, the pathophysiology remains poorly understood. Here, we show that both constitutive and induced genetic deletion of the gene encodi...

2014
John-Erik Mathisen Jan Ketil Arnulf

This study builds on research on mindsets from laboratory research to develop and test a measurement scale for entrepreneurial mindsets. A three-dimensional scale was constructed measuring elaborating mindsets, implemental mindsets, and compulsiveness about business ideas. Exploratory and confirmatory factor analyses support the claim that these three latent variables may be reliably measured. ...

Journal: :Neuropharmacology 2012
T J Bussey A Holmes L Lyon A C Mar K A L McAllister J Nithianantharajah C A Oomen L M Saksida

We describe a touchscreen method that satisfies a proposed 'wish-list' of desirables for a cognitive testing method for assessing rodent models of schizophrenia. A number of tests relevant to schizophrenia research are described which are currently being developed and validated using this method. These tests can be used to study reward learning, memory, perceptual discrimination, object-place a...

Journal: :CNS spectrums 2014
Stephen M Stahl

The year 2014 was a great year for CNS Spectrums. Following our transition year to our new publisher, Cambridge University Press, in 2012, we have now had 2 years of publishing 6 bimonthly issues plus a seventh CME issue each December, also including the abstracts of the Annual Neuroscience Education Institute’s (NEI) Psychopharmacology Congress. The numbers of articles and pages have progressi...

Journal: :Neuroscience & Biobehavioral Reviews 2021

Recurring episodes of excessive food intake in binge eating disorder can be understood through the lens behavioral control systems: patients repeat maladaptive behaviors against their explicit intent. Self-report measures show enhanced impulsivity and compulsivity (BE) but are agnostic as to processes that might lead impulsive compulsive behavior moment. Task-based neurocognitive investigations...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید