Drug discovery and development is a very challenging, expensive time-consuming process. Impressive technological advances in computer sciences molecular biology have made it possible to use computer-aided drug design (CADD) methods various stages of the pipeline. Nowadays, CADD presents an efficacious indispensable tool, widely used medicinal chemistry, lead rational synthesis novel compounds. ...

This paper presents a control model of the hydroforming and the dual hydroforming process of a tube. The theoretical part includes calculations to measure the change in tube thickness through the developed process. The hydroforming and the dual hydroforming processes are simulated in the SOLIDSIMULATION software and the static and the dynamic simulations are modeled. The obtained results for th...

Often in modeling the engineering optimization design problems, the value of objective function(s) is not clearly defined in terms of design variables. Instead it is obtained by some numerical analysis such as FE structural analysis, fluid mechanic analysis, and thermodynamic analysis, etc. Yet, the numerical analyses are considerably time consuming to obtain the final value of objective functi...