Inotropic effects of electric currents applied during the refractory period have been reported in cardiac muscle in vitro using voltage-clamp techniques. We investigated how electric currents modulate cardiac contractility in normal canine hearts in vivo. Six dogs were instrumented to measure regional segment length, ventricular volume (sonomicrometry), and ventricular pressure. Cardiac contrac...

introductioin Cerebral cavernous malformation (CCM), also known as cavernous angioma, is a type of vascular malformation in the central nervous system. To date, rare cases of CCM and seizure have been reported in pregnancies. Nowadays, the management of such condition in pregnancy is still a challenge due to lacking of experiences. We presented a case of pregnant woman with CCM combined with ep...

Glioblastomas (GBMs) are the most common and aggressive malignant primary brain tumors found in humans. In high-grade gliomas, vasculogenic mimicry (VM) is often detected. VM is the formation of de novo vascular networks by highly invasive tumor cells, instead of endothelial cells. An understanding of the mechanisms of VM formation will contribute to the targeted therapy of GBMs. In the present...

Las aflatoxinas son metabolitos secundarios tóxicos para salud humana y animal producidos por Aspergillus flavus, que contaminan a los alimentos lo largo de la cadena productiva. Conocer caracterizar población fúngica presente en nos sirve estimar riesgo diseñar medidas mitigarlo. Siendo así, el objetivo este trabajo es potencial toxigénico aislados provenientes maíz modelos in vitro. Para tal ...

Let Γ̄ be the Picard modular group of an imaginary quadratic number field k and let D be the associated symmetric space. Let Γ ⊂ Γ̄ be a congruence subgroup. We describe a method to compute the integral cohomology of the locally symmetric space Γ\D. The method is implemented for the cases k = Q(i) and k = Q( √ −3), and the cohomology is computed for various Γ.

IMPORTANCE People with substance dependence have health consequences, high health care utilization, and frequent comorbidity but often receive poor-quality care. Chronic care management (CCM) has been proposed as an approach to improve care and outcomes. OBJECTIVE To determine whether CCM for alcohol and other drug dependence improves substance use outcomes compared with usual primary care. ...

Four estrous beagles were inseminated with 1 x 10(8) sperm into both the right and left uterine horns, and the uterine horn and oviduct on one side were removed under anesthesia after 7 hr and 24 hr, respectively. The lumen of the uterine horns and oviducts was flushed with canine capacitation medium (CCM), and movement of the sperm in CCM was assessed by phase-contrast microscopy. In a second ...

PURPOSE The purpose of this study is to evaluate the stability of interface between Co-Cr-Mo (CCM) UCLA abutment and external hex implant. MATERIALS AND METHODS Sixteen external hex implant fixtures were assigned to two groups (CCM and Gold group) and were embedded in molds using clear acrylic resin. Screw-retained prostheses were constructed using CCM UCLA abutment and Gold UCLA abutment. Th...