Introduction and aims: Leukemia is a heterogeneous group of hematological disorders that made up several diverse biologically distinct subgroups. the eleventh tenth most common cause cancer morbidity mortality worldwide, respectively. There are insufficient data on parameters counts leukemia in Yemen. This cross-sectional study aims to determine for children with leukemia.

Actas Dermosifiliogr. 2007;98:291-5 294 transferase, CD30, CD3, CD20, serum protein S-100, CD119, and CD34. Based on these findings, the patient was diagnosed with leukemia cutis (LC). Specifically, the diagnosis was chloroma, or infiltration by myeloid or granulocytic sarcoma. The patient was referred to the reference hospital for pediatric oncology, Hospital La Fe de Valencia, Spain, where a ...

homogeneously staining regions (hsr) or double minute chromosomes (dmin) are autonomously replicating extra-chromosomal elements that are frequently associated with gene amplifi cation in a variety of cancers. the diagnosis of leukemia patients was based on characterization of the leukemic cells obtained from bone marrow cytogenetics. this study report two cases, one with acute myeloblastic leu...

OBJECTIVE To investigate the association between neonatal phototherapy use and childhood cancer. METHODS This retrospective cohort study included 499 621 children born at ≥35 weeks' gestation from 1995 to 2011 in Kaiser Permanente Northern California hospitals, who survived to hospital discharge and were followed ≥60 days. We obtained data on home and inpatient phototherapy, covariates, and c...

fuzzy expert systems are one of the most practical intelligent models with the high potential for managing uncertainty associated to the medical diagnosis. in this paper, a fuzzy inference system (fis) for diagnosing of acute lymphocytic leukemia in children has been introduced. the fuzzy expert system applies mamdani reasoning model that has high interpretability to explain system results to e...

chronic lymphocytic leukemia (cll) and chronic myeloid leukemia (cml) are the most common leukemias of the elderly (>43 year). however, the sequential occurrence of cml followed by cll in the same patient is extremely rare. in our report, a 52-year-old female was diagnosed with cll (type of bone marrow (bm) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months ...

Fanconi anemia (FA) is an autosomal recessive condition associated with bone marrow failure (BMF) leading to death or hematopoietic stem cell transplantation, acute myeloid leukemia (AML), and solid tumors (STs). It is unclear which patients are most likely to develop each outcome. From a cohort of 144 North American patients with FA, we calculated individualized risks of each outcome, given th...

Gain-of-function mutations in SHP-2/PTPN11 cause Noonan syndrome, a human developmental disorder. Noonan syndrome is characterized by proportionate short stature, facial dysmorphia, increased risk of leukemia, and congenital heart defects in approximately 50% of cases. Congenital heart abnormalities are common in Noonan syndrome, but the signaling pathway(s) linking gain-of-function SHP-2 mutan...